Sheehan David V, Giddens Jennifer M, Sheehan Ivan Sascha
Dr. D. Sheehan is Distinguished University Health Professor Emeritus at the University of South Florida College of Medicine, Tampa, Florida; J. Giddens is the Co-founder of the Tampa Center for Research on Suicidality, Tampa, Florida; and Dr. I. S. Sheehan is Assistant Professor and Graduate Program Director, School of Public and International Affairs, University of Baltimore, Baltimore, Maryland.
Innov Clin Neurosci. 2014 Sep;11(9-10):93-140.
There is a need for a choice of scales to evaluate the full range of suicidal phenomena. Such scales must be capable of use as both safety and efficacy outcome measures in research and in clinical settings. Central to the success in finding and developing effective anti-suicidal medications is having a sensitive suicidality scale that can detect an efficacy signal in conventional sample sizes used in clinical trials. The Sheehan-Suicidality Tracking Scale was developed for these purposes. This article provides a 2014 status update on the scale's progress, its use, and its properties. The authors review why and how the scale was developed; the scale structure, versions, and properties; the trials in which it was used; the time frames accommodated; its validation and reliability studies; its utility in screening and assessment; its utility in assessing treatment-emergent suicidal adverse events; its use as an efficacy outcome measure; its availability in self-rated and clinician-rated forms; the availability and linguistic validation of pediatric versions; linguistic validation in other languages; how it compares with global ratings of suicidality; and its possible utility and applications.
需要有多种量表来评估自杀现象的全范围。此类量表必须能够在研究和临床环境中用作安全性和有效性结局指标。找到并开发有效的抗自杀药物成功的关键在于拥有一个敏感的自杀倾向量表，该量表能够在临床试验中使用的常规样本量中检测到疗效信号。希恩自杀倾向追踪量表就是为此目的而开发的。本文提供了该量表在2014年的进展、使用情况及其特性的最新信息。作者回顾了该量表开发的原因和方式；量表的结构、版本和特性；使用该量表的试验；涵盖的时间范围；其验证和可靠性研究；其在筛查和评估中的效用；其在评估治疗中出现的自杀性不良事件中的效用；其作为疗效结局指标的用途；自评和临床医生评定形式的可用性；儿科版本的可用性和语言验证；其他语言中的语言验证；它与自杀倾向整体评定的比较；以及其可能的效用和应用。
