Dipartimento di Scienze per la promozione della salute e materno-infantile, Università di Palermo, Italy.
Dipartimento di Discipline chirurgiche, oncologiche e stomatologiche, Università di Palermo, Italy.
Int J Infect Dis. 2015 Apr;33:5-6. doi: 10.1016/j.ijid.2014.12.020. Epub 2014 Dec 15.
Visceral leishmaniasis due to Leishmania infantum is a vector-borne zoonotic disease transmitted by sand fly bites endemic in rural or periurban areas of the Mediterranean basin. Pregnancy is accompanied by changes in immune response, mainly a decrease in cellular immunity and a proportional increase in humoral immunity. These physiological events result in increased risk of infection by pathogens whose immunity is based on a T-helper 1 predominant response. We describe a case of visceral leishmaniasis and pulmonary tuberculosis diagnosed in a post-partum woman four days after delivery. The diagnosis of leishmaniasis should be considered in pregnant women with fever and haematologic abnormalities in endemic regions or if a history of exposure in endemic areas is reported.
内脏利什曼病是由利什曼原虫引起的一种虫媒传染病，通过沙蝇叮咬传播，在地中海盆地的农村或城郊地区流行。妊娠伴随着免疫反应的变化，主要是细胞免疫的下降和体液免疫的相应增加。这些生理变化导致感染病原体的风险增加，而这些病原体的免疫是基于辅助性 T 细胞 1 型反应为主。我们描述了一例产后四天的产妇并发内脏利什曼病和肺结核。在流行地区，如果孕妇出现发热和血液学异常，或有在流行地区接触史，应考虑利什曼病的诊断。
