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肺动脉高压及其主要亚型的CT特征：来自ASPIRE注册研究的292例患者的系统CT评估

CT features of pulmonary arterial hypertension and its major subtypes: a systematic CT evaluation of 292 patients from the ASPIRE Registry.

作者信息

Rajaram S, Swift A J, Condliffe R, Johns C, Elliot C A, Hill C, Davies C, Hurdman J, Sabroe I, Wild J M, Kiely D G

机构信息

Academic Unit of Radiology, University of Sheffield, Sheffield, UK.

Sheffield Pulmonary Vascular Disease Unit and Academic Department of Respiratory Medicine, Royal Hallamshire Hospital, Sheffield, UK.

出版信息

Thorax. 2015 Apr;70(4):382-7. doi: 10.1136/thoraxjnl-2014-206088. Epub 2014 Dec 18.

DOI:10.1136/thoraxjnl-2014-206088
PMID:25523307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4392204/
Abstract

We evaluated the prevalence and prognostic value of CT-pulmonary angiographic (CTPA) measures in 292 treatment naive patients with pulmonary arterial hypertension (PAH). Pulmonary artery calcification (13%) and thrombus (10%) were exclusively seen in PAH-congenital heart disease. Oesophageal dilation (46%) was most frequent in PAH-systemic sclerosis. Ground glass opacification (GGO) (41%), pericardial effusion (38%), lymphadenopathy (19%) and pleural effusion (11%) were common. On multivariate analysis, inferior vena caval area, the presence of pleural effusion and septal lines predicted outcome. In PAH, CTPA provides diagnostic and prognostic information. In addition, the presence of GGO on a CT performed for unexplained breathlessness should alert the physician to the possibility of PAH.

摘要

我们评估了292例初治肺动脉高压（PAH）患者的CT肺血管造影（CTPA）测量指标的患病率及预后价值。肺动脉钙化（13%）和血栓（10%）仅见于先天性心脏病相关性PAH。食管扩张（46%）在系统性硬化症相关性PAH中最为常见。磨玻璃影（GGO）（41%）、心包积液（38%）、淋巴结肿大（19%）和胸腔积液（11%）较为常见。多因素分析显示，下腔静脉面积、胸腔积液的存在及间隔线可预测预后。在PAH中，CTPA可提供诊断及预后信息。此外，因不明原因呼吸困难行CT检查时发现GGO应提醒医生注意PAH的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/597cb62dd479/thoraxjnl-2014-206088f06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/69af1aaf0c38/thoraxjnl-2014-206088f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/771f60d4a91d/thoraxjnl-2014-206088f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/15210060d624/thoraxjnl-2014-206088f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/248bfd6ebcfa/thoraxjnl-2014-206088f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/c22c560f41cf/thoraxjnl-2014-206088f05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/597cb62dd479/thoraxjnl-2014-206088f06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/69af1aaf0c38/thoraxjnl-2014-206088f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/771f60d4a91d/thoraxjnl-2014-206088f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/15210060d624/thoraxjnl-2014-206088f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/248bfd6ebcfa/thoraxjnl-2014-206088f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/c22c560f41cf/thoraxjnl-2014-206088f05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d8/4392204/597cb62dd479/thoraxjnl-2014-206088f06.jpg

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