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高粘度骨水泥与低粘度骨水泥椎体成形术治疗重度骨质疏松性椎体压缩骨折的比较

A comparison of high viscosity bone cement and low viscosity bone cement vertebroplasty for severe osteoporotic vertebral compression fractures.

作者信息

Zhang Liang, Wang Jingcheng, Feng Xinmin, Tao Yuping, Yang Jiandong, Wang Yongxiang, Zhang Shengfei, Cai Jun, Huang Jijun

机构信息

Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.

Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.

出版信息

Clin Neurol Neurosurg. 2015 Feb;129:10-6. doi: 10.1016/j.clineuro.2014.11.018. Epub 2014 Dec 4.

DOI:10.1016/j.clineuro.2014.11.018
PMID:25524481
Abstract

OBJECTIVE

To compare the clinical outcome and complications of high viscosity and low viscosity poly-methyl methacrylate bone cement PVP for severe OVCFs.

METHODS

From December 2010 to December 2012, 32 patients with severe OVCFs were randomly assigned to either group H using high viscosity cement (n=14) or group L using low viscosity cement (n=18). The clinical outcomes were assessed by the Visual Analog Scale (VAS), Oswestry Disability Index (ODI), Short Form-36 General Health Survey (SF-36), kyphosis Cobb's angle, vertebral height, and complications.

RESULTS

Significant improvement in the VAS, ODI, SF-36 scores, kyphosis Cobb's angle, and vertebral height were noted in both the groups, and there were no significant differences between the two groups. Cement leakage was seen less in group H. Postoperative assessment using computed tomography identified cement leakage in 5 of 17 (29.4%) vertebrae in group H and in 15 of 22 (68.2%) vertebrae in group L (P=0.025).

CONCLUSIONS

The PVP using high viscosity bone cement can provide the same clinical outcome and fewer complications compared with PVP using low viscosity bone cement.

摘要

目的

比较高粘度和低粘度聚甲基丙烯酸甲酯骨水泥经皮椎体成形术(PVP)治疗重度骨质疏松性椎体压缩骨折(OVCFs)的临床疗效及并发症。

方法

2010年12月至2012年12月,32例重度OVCFs患者被随机分为使用高粘度骨水泥的H组(n = 14)和使用低粘度骨水泥的L组(n = 18)。通过视觉模拟评分法(VAS)、Oswestry功能障碍指数(ODI)、简短健康调查问卷36项(SF - 36)、后凸Cobb角、椎体高度及并发症评估临床疗效。

结果

两组患者的VAS、ODI、SF - 36评分、后凸Cobb角及椎体高度均有显著改善,两组间差异无统计学意义。H组骨水泥渗漏较少。术后CT评估发现,H组17个椎体中有5个(29.4%)发生骨水泥渗漏,L组22个椎体中有15个(68.2%)发生骨水泥渗漏(P = 0.025)。

结论

与使用低粘度骨水泥的PVP相比,使用高粘度骨水泥的PVP能提供相同的临床疗效且并发症更少。

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