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高黏度骨水泥与标准骨水泥椎体成形术治疗 Kummell 病的临床效果分析。

Clinical effect analysis of vertebroplasty with high viscosity and standard bone cement for Kummell disease.

机构信息

Department of Orthopedics, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.

Department of Orthopedics, The Hospital of Zhangping City, Zhangping, China.

出版信息

Medicine (Baltimore). 2024 Oct 4;103(40):e39960. doi: 10.1097/MD.0000000000039960.

Abstract

This study aims to observe and compare the effects of high-viscosity bone cement versus standard bone cement on the postoperative outcomes of percutaneous vertebroplasty (PVP) in patients with Kummell disease. A retrospective analysis was conducted on 135 patients with Kummell disease who underwent PVP between January 2019 and May 2023. Patients were divided into 2 groups: the high-viscosity group (group H, 63 cases) received high-viscosity bone cement during surgery, while the standard group (group S, 72 cases) received standard bone cement. Surgery duration, bone cement volume, bone cement leakage rate, as well as preoperative and postoperative evaluations using the Visual Analogue Scale (VAS) for pain, Oswestry Disability Index (ODI), anterior vertebral height, and kyphotic Cobb angle were recorded and compared between the 2 groups. In the group H, significant improvements were observed in VAS scores, ODI, anterior vertebral height, and Cobb angle at 24 hours, 3 months, and 1 year postoperatively compared to preoperative values (P < .01). In the group S, VAS scores and ODI showed significant improvement at 24 hours, 3 months, and 1 year postoperatively (P < .01), but there were no significant differences in anterior vertebral height or Cobb angle compared to preoperative values (P > .05). Comparatively, the group H demonstrated superior outcomes in terms of bone cement volume, leakage rate, recovery of anterior vertebral height, and Cobb angle correction at 24 hours, 3 months, and 1 year postoperatively (P < .05). However, there were no significant differences between the 2 groups in terms of surgery duration, VAS scores, and ODI at the same time points (P > .05). PVP is an effective treatment for Kummell disease, providing significant pain relief and improved spinal function. The use of high-viscosity bone cement allows for greater volume infusion, better restoration of vertebral height, and correction of deformities, while also reducing the risk of cement leakage.

摘要

本研究旨在观察和比较高黏度骨水泥与标准骨水泥对 Kummell 病患者经皮椎体成形术(PVP)术后结局的影响。对 2019 年 1 月至 2023 年 5 月间接受 PVP 治疗的 135 例 Kummell 病患者进行回顾性分析。患者分为 2 组:高黏度组(H 组,63 例)术中使用高黏度骨水泥,标准组(S 组,72 例)使用标准骨水泥。记录并比较两组患者的手术时间、骨水泥用量、骨水泥渗漏率,以及术前和术后疼痛视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)、椎体前缘高度和后凸 Cobb 角的评估结果。H 组患者术后 24 小时、3 个月和 1 年时 VAS 评分、ODI、椎体前缘高度和 Cobb 角均较术前显著改善(P<0.01)。S 组患者术后 24 小时、3 个月和 1 年时 VAS 评分和 ODI 均较术前显著改善(P<0.01),但与术前相比,椎体前缘高度和 Cobb 角无显著差异(P>0.05)。与 S 组相比,H 组患者术后 24 小时、3 个月和 1 年时骨水泥用量、渗漏率、椎体前缘高度恢复和 Cobb 角矫正均更优(P<0.05),但两组患者在手术时间、VAS 评分和 ODI 方面的差异无统计学意义(P>0.05)。PVP 是治疗 Kummell 病的有效方法,可显著缓解疼痛,改善脊柱功能。使用高黏度骨水泥可增加骨水泥注入量,更好地恢复椎体高度,矫正畸形,同时降低骨水泥渗漏风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d4d/11460861/52e288192f46/medi-103-e39960-g001.jpg

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