Skoch Jesse, Kobylanski Kelly, Rice Jeffrey M, Baaj Ali A
Department of Surgery, Division of Neurological Surgery, The University of Arizona Medical Center, Tucson, Arizona, USA.
Department of Pathology, The University of Arizona Medical Center, Tucson, Arizona, USA.
Surg Neurol Int. 2014 Nov 21;5:161. doi: 10.4103/2152-7806.145205. eCollection 2014.
There are few cases of choriocarcinoma metastases to the spine that have been reported. Most occurrences are in women with the gestational form of the tumor, and these now exhibit a very high remission rate with chemotherapeutic treatment, typically circumventing the need for spinal surgery.
In an effort to better understand treatment options for those rare instances when choriocarcinoma does find its way into the spine, we have synthesized a comprehensive literature review on the clinical cases of choriocarcinoma spinal metastases. We also describe our unique experience and decision-making involving the first reported case of surgical treatment of non-gestational choriocarcinoma spinal metastases in a male patient.
Spinal surgery has a limited role in metastatic choriocarcinoma, but there is the potential for improving neurologic decline even in the rare and aggressive male variant of this disease.