Wheeler Thomas L, Illston Jana D, Markland Alayne D, Goode Patricia S, Richter Holly E
Department of Obstetrics and Gynecology, University of South Carolina School of Medicine-Greenville, Greenville, SC.
Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, Birmingham, AL.
Open J Obstet Gynecol. 2014 Oct;4(14):809-816. doi: 10.4236/ojog.2014.414112.
Urinary incontinence (UI) impacts all aspects of life activities. This study aims to characterize change in mobility within the community utilizing the Life Space Assessment (LSA) questionnaire in women undergoing non-surgical UI treatment.
Prospective cohort study, performed from July 2007 to March 2009, which followed women seeking non-surgical UI treatment and assessed their mobility and symptoms using LSA, Urogenital Distress Inventory (UDI-6), and Incontinence Impact Questionnaire (IIQ-7) at baseline and 2, 6, and 12 months post-treatment. Estimated Percent Improvement (EPI) and Patient Satisfaction Question (PSQ) were obtained post-treatment.
Outpatient tertiary-care clinic.
70 ambulatory, community-dwelling women, aged 65 years or older, seeking non-surgical care for UI.
Multi-component behavioral and/or pharmacologic therapies.
We hypothesized LSA would improve with treatment. Repeated measures analysis with Tukey's HSD and backwards selection linear regression model were performed.
LSA score decreased from baseline to 2 months (mean±SD; 63±29 to 56±28, p<0.001) and was sustained at 6 and 12 months (54±28, 54±28). UDI scores improved from 36±23 to 25±24, p<0.001, at 2 months, and improvement persisted at 6 and 12 months (22±22, 21±24). Improvements in UDI and patient perceived improvement in UI were not associated with LSA change. Age, race, and depression impacted LSA, which decreased 1-point for each additional year of age (p=0.004), 6-points for each point higher on the Geriatric Depression Scale (GDS) (p=0.002), and 6-points for African American race (p=0.048).
Decreased mobility represented by LSA was related to age, depression, and race, but not UI symptom improvement.
尿失禁(UI)会影响生活活动的各个方面。本研究旨在利用生活空间评估(LSA)问卷,对接受非手术尿失禁治疗的女性在社区中的活动能力变化进行特征描述。
前瞻性队列研究,于2007年7月至2009年3月进行,跟踪寻求非手术尿失禁治疗的女性,并在基线以及治疗后2个月、6个月和12个月时,使用LSA、泌尿生殖系统困扰量表(UDI-6)和尿失禁影响问卷(IIQ-7)评估她们的活动能力和症状。治疗后获取估计改善百分比(EPI)和患者满意度问题(PSQ)。
门诊三级护理诊所。
70名65岁及以上、寻求非手术尿失禁护理的社区活动女性。
多成分行为和/或药物治疗。
我们假设LSA会随着治疗而改善。采用Tukey's HSD重复测量分析和向后选择线性回归模型。
LSA评分从基线到2个月时下降(均值±标准差;63±29降至56±28,p<0.001),并在6个月和12个月时维持在该水平(54±28,54±28)。UDI评分在2个月时从36±23改善至25±24,p<0.001,且在6个月和12个月时持续改善(22±22,21±24)。UDI的改善以及患者感知到的尿失禁改善与LSA变化无关。年龄、种族和抑郁会影响LSA,年龄每增加一岁,LSA下降1分(p=0.004),老年抑郁量表(GDS)每升高1分,LSA下降6分(p=0.002),非裔美国人种族使LSA下降6分(p=0.048)。
LSA所代表的活动能力下降与年龄、抑郁和种族有关,但与尿失禁症状改善无关。