• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

草鱼（Ctenopharyngodon idellus）和脆化草鱼的基因表达谱分析。

Gene Expression Profiling of Grass Carp (Ctenopharyngodon idellus) and Crisp Grass Carp.

机构信息

Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation, Ministry of Agriculture, Pearl River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510380, China.

出版信息

Int J Genomics. 2014;2014:639687. doi: 10.1155/2014/639687. Epub 2014 Nov 30.

DOI:10.1155/2014/639687
PMID:25525591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4266764/
Abstract

Grass carp (Ctenopharyngodon idellus) is one of the most important freshwater fish that is native to China, and crisp grass carp is a kind of high value-added fishes which have higher muscle firmness. To investigate biological functions and possible signal transduction pathways that address muscle firmness increase of crisp grass carp, microarray analysis of 14,900 transcripts was performed. Compared with grass carp, 127 genes were upregulated and 114 genes were downregulated in crisp grass carp. Gene ontology (GO) analysis revealed 30 GOs of differentially expressed genes in crisp grass carp. And strong correlation with muscle firmness increase of crisp grass carp was found for these genes from differentiation of muscle fibers and deposition of ECM, and also glycolysis/gluconeogenesis pathway and calcium metabolism may contribute to muscle firmness increase. In addition, a number of genes with unknown functions may be related to muscle firmness, and these genes are still further explored. Overall, these results had been demonstrated to play important roles in clarifying the molecular mechanism of muscle firmness increase in crisp grass carp.

摘要

草鱼（Ctenopharyngodon idellus）是原产于中国的最重要的淡水鱼类之一，而脆肉鲩是一种高附加值的鱼类，其肌肉硬度更高。为了研究提高脆肉鲩肌肉硬度的生物学功能和可能的信号转导途径，我们对 14900 个转录本进行了微阵列分析。与草鱼相比，脆肉鲩中有 127 个基因上调，114 个基因下调。GO 分析显示，脆肉鲩中有 30 个差异表达基因的 GO。与脆肉鲩肌肉硬度增加密切相关的这些基因来自肌纤维分化和细胞外基质沉积，以及糖酵解/糖异生途径和钙代谢可能有助于肌肉硬度增加。此外，一些具有未知功能的基因可能与肌肉硬度有关，这些基因仍在进一步探索中。总的来说，这些结果对于阐明脆肉鲩肌肉硬度增加的分子机制具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/4266764/e769f9b52b0b/IJG2014-639687.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/4266764/44eb8be6be08/IJG2014-639687.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/4266764/b45cad69cc2d/IJG2014-639687.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/4266764/e769f9b52b0b/IJG2014-639687.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/4266764/44eb8be6be08/IJG2014-639687.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/4266764/b45cad69cc2d/IJG2014-639687.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a89/4266764/e769f9b52b0b/IJG2014-639687.003.jpg

相似文献

1
Gene Expression Profiling of Grass Carp (Ctenopharyngodon idellus) and Crisp Grass Carp.草鱼（Ctenopharyngodon idellus）和脆化草鱼的基因表达谱分析。
Int J Genomics. 2014;2014:639687. doi: 10.1155/2014/639687. Epub 2014 Nov 30.
2
Transcriptome analysis revealed changes of multiple genes involved in muscle hardness in grass carp (Ctenopharyngodon idellus) fed with faba bean meal.转录组分析显示，饲喂蚕豆粕的草鱼（Ctenopharyngodon idellus）肌肉硬度相关的多个基因发生变化。
Food Chem. 2020 Jun 1;314:126205. doi: 10.1016/j.foodchem.2020.126205. Epub 2020 Jan 14.
3
Molecular cloning of type I collagen cDNA and nutritional regulation of type I collagen mRNA expression in grass carp.草鱼I型胶原蛋白cDNA的分子克隆及I型胶原蛋白mRNA表达的营养调控
J Anim Physiol Anim Nutr (Berl). 2014 Aug;98(4):755-65. doi: 10.1111/jpn.12132. Epub 2013 Oct 15.
4
Identification of the Dominant Microbial Species of Spoiled Crisp Grass Carp ( Ctenopharyngodon idellus C. et V.) and Grass Carp ( Ctenopharyngodon idellus) Fillets during Cold Storage by Culture-Independent 16S rDNA Sequence Analysis.利用非培养 16S rDNA 序列分析鉴定冷藏过程中变质脆化草鱼（Ctenopharyngodon idellus C. et V.）和草鱼（Ctenopharyngodon idellus）鱼片的优势微生物种属。
J Food Prot. 2018 Jan;81(1):84-92. doi: 10.4315/0362-028X.JFP-17-141.
5
Comparative genome-wide methylation analysis reveals epigenetic regulation of muscle development in grass carp () fed with whole faba bean.比较全基因组甲基化分析揭示了饲喂完整蚕豆对草鱼肌肉发育的表观遗传调控。
PeerJ. 2022 Nov 21;10:e14403. doi: 10.7717/peerj.14403. eCollection 2022.
6
Multi-Omics Sequencing Provides Insights Into Age-Dependent Susceptibility of Grass Carp () to Reovirus.多组学测序揭示了草鱼（）对呼肠孤病毒年龄依赖性易感性的机制。
Front Immunol. 2021 Jun 17;12:694965. doi: 10.3389/fimmu.2021.694965. eCollection 2021.
7
Proteomic and metabolomic basis for improved textural quality in crisp grass carp (Ctenopharyngodon idellus C.et V) fed with a natural dietary pro-oxidant.以天然膳食促氧化剂喂养的脆肉鲩（Ctenopharyngodon idellus C.et V）肉质改善的蛋白质组学和代谢组学基础
Food Chem. 2020 Apr 24;325:126906. doi: 10.1016/j.foodchem.2020.126906.
8
Quantitative phosphoproteomic analysis of soft and firm grass carp muscle.软质草鱼和硬质草鱼肌肉的定量磷酸化蛋白质组学分析。
Food Chem. 2020 Jan 15;303:125367. doi: 10.1016/j.foodchem.2019.125367. Epub 2019 Aug 16.
9
Effect of Ultrastructure on Changes of Textural Characteristics between Crisp Grass Carp (Ctenopharyngodon Idellus C.Et V) and Grass Carp (Ctenopharyngodon Idellus) Inducing Heating Treatment.超微结构对脆化草鱼（Ctenopharyngodon Idellus C.Et V）和草鱼（Ctenopharyngodon Idellus）经加热处理后质地特性变化的影响。
J Food Sci. 2016 Feb;81(2):E404-11. doi: 10.1111/1750-3841.13189. Epub 2016 Jan 12.
10
Transcriptomic and biochemical analyses revealed the improved growth, lipid metabolism, and flesh quality of grass carp (Ctenopharyngodon idellus) by dietary Eucommia ulmoides bark and leaf supplementation.转录组学和生化分析显示，日粮杜仲树皮和杜仲叶补充剂可改善草鱼（Ctenopharyngodon idellus）的生长、脂质代谢和肉质。
J Anim Sci. 2022 Oct 1;100(10). doi: 10.1093/jas/skac250.

引用本文的文献

1
EccDNA Analysis Provides Novel Insights Into the Molecular Mechanism of Firmness of Fish Fillet.染色体外环状DNA分析为鱼片硬度的分子机制提供了新见解。
Food Sci Nutr. 2025 May 13;13(5):e70268. doi: 10.1002/fsn3.70268. eCollection 2025 May.
2
Unveiling the Molecular Mechanisms Regulating Muscle Elasticity in the Large Yellow Croaker: Insights from Transcriptomics and Metabolomics.揭示大黄鱼肌肉弹性调节的分子机制：转录组学和代谢组学的见解。
Int J Mol Sci. 2024 Oct 11;25(20):10924. doi: 10.3390/ijms252010924.
3
Targeted metabolomics of muscle amino acid profles and hepatic transcriptomics analyses in grass carp () fed with broad beans.

本文引用的文献

1
Molecular cloning of type I collagen cDNA and nutritional regulation of type I collagen mRNA expression in grass carp.草鱼I型胶原蛋白cDNA的分子克隆及I型胶原蛋白mRNA表达的营养调控
J Anim Physiol Anim Nutr (Berl). 2014 Aug;98(4):755-65. doi: 10.1111/jpn.12132. Epub 2013 Oct 15.
2
Gene expression profiling of soft and firm Atlantic salmon fillet.大西洋三文鱼软、硬鱼片的基因表达谱分析。
PLoS One. 2012;7(6):e39219. doi: 10.1371/journal.pone.0039219. Epub 2012 Jun 20.
3
Fish under exercise.运动中的鱼类。
投喂蚕豆的草鱼肌肉氨基酸谱靶向代谢组学及肝脏转录组学分析
Heliyon. 2024 Sep 24;10(19):e38323. doi: 10.1016/j.heliyon.2024.e38323. eCollection 2024 Oct 15.
4
Expression Patterns of , , and Reveal Insights into Heterosis for Growth of Hybrid Offspring between and .和 的表达模式揭示了 和 杂交后代生长杂种优势的见解。
Genes (Basel). 2024 Jul 19;15(7):945. doi: 10.3390/genes15070945.
5
Comparative genome-wide methylation analysis reveals epigenetic regulation of muscle development in grass carp () fed with whole faba bean.比较全基因组甲基化分析揭示了饲喂完整蚕豆对草鱼肌肉发育的表观遗传调控。
PeerJ. 2022 Nov 21;10:e14403. doi: 10.7717/peerj.14403. eCollection 2022.
6
Increased accuracy of genomic predictions for growth under chronic thermal stress in rainbow trout by prioritizing variants from GWAS using imputed sequence data.通过使用推算序列数据对全基因组关联研究（GWAS）中的变异进行优先级排序，提高虹鳟在慢性热应激下生长的基因组预测准确性。
Evol Appl. 2021 May 18;15(4):537-552. doi: 10.1111/eva.13240. eCollection 2022 Apr.
7
Size Effects of Microplastics on Embryos and Observation of Toxicity Kinetics in Larvae of Grass Carp ().微塑料对草鱼胚胎的尺寸效应及幼鱼毒性动力学观察
Toxics. 2022 Feb 7;10(2):76. doi: 10.3390/toxics10020076.
8
Effects of Dietary Paper Mulberry on Growth Performance and Muscle Quality of Grass Carp ().饲料中添加构树对草鱼生长性能和肌肉品质的影响（）。 （括号部分原文缺失内容）
Animals (Basel). 2021 Jun 2;11(6):1655. doi: 10.3390/ani11061655.
9
Intestinal Microbiota of Grass Carp Fed Faba Beans: A Comparative Study.投喂蚕豆的草鱼肠道微生物群：一项比较研究。
Microorganisms. 2019 Oct 17;7(10):465. doi: 10.3390/microorganisms7100465.
10
Lipid accumulation in grass carp (Ctenopharyngodon idellus) fed faba beans (Vicia faba L.).投喂蚕豆的草鱼（Ctenopharyngodon idellus）体内的脂质积累。
Fish Physiol Biochem. 2019 Apr;45(2):631-642. doi: 10.1007/s10695-018-0589-7. Epub 2018 Nov 20.
Fish Physiol Biochem. 2011 Jun;37(2):259-72. doi: 10.1007/s10695-011-9505-0. Epub 2011 May 25.
4
Dystrophin-deficient zebrafish feature aspects of the Duchenne muscular dystrophy pathology.肌营养不良症相关病理特征出现在肌营养不良蛋白缺陷型斑马鱼中。
Neuromuscul Disord. 2010 Dec;20(12):826-32. doi: 10.1016/j.nmd.2010.08.004. Epub 2010 Sep 17.
5
Myostatin directly regulates skeletal muscle fibrosis.肌肉生长抑制素直接调节骨骼肌纤维化。
J Biol Chem. 2008 Jul 11;283(28):19371-8. doi: 10.1074/jbc.M802585200. Epub 2008 May 3.
6
Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation.骨骼肌细胞表达促纤维化细胞因子结缔组织生长因子（CTGF/CCN2），该因子可诱导其去分化。
J Cell Physiol. 2008 May;215(2):410-21. doi: 10.1002/jcp.21324.
7
Microarray analysis of gene expression in the blue catfish liver reveals early activation of the MHC class I pathway after infection with Edwardsiella ictaluri.斑点叉尾鮰肝脏基因表达的微阵列分析显示，感染鮰爱德华氏菌后MHC I类途径被早期激活。
Mol Immunol. 2008 Jan;45(2):553-66. doi: 10.1016/j.molimm.2007.05.012. Epub 2007 Jun 27.
8
Role of the SDF-1/CXCR4 axis in the pathogenesis of lung injury and fibrosis.SDF-1/CXCR4轴在肺损伤和纤维化发病机制中的作用。
Am J Respir Cell Mol Biol. 2007 Sep;37(3):291-9. doi: 10.1165/rcmb.2006-0187OC. Epub 2007 Apr 26.
9
Microarray studies of gene expression in fish.鱼类基因表达的微阵列研究。
OMICS. 2006 Winter;10(4):474-89. doi: 10.1089/omi.2006.10.474.
10
The first intron of the human alpha2(I) collagen gene (COL1A2) contains a novel interferon-gamma responsive element.人类α2（I）胶原蛋白基因（COL1A2）的第一个内含子包含一个新型的γ干扰素反应元件。
Matrix Biol. 2007 Apr;26(3):185-9. doi: 10.1016/j.matbio.2006.10.009. Epub 2006 Nov 10.