Johnson Linda M, Choyke Peter L, Figg William D, Turkbey Baris
Molecular Pharmacology Section, Medical Oncology Branch, National Cancer Institute, Bethesda, MD 20852, USA.
Molecular Imaging Program, National Cancer Institute, Bethesda, MD 20852, USA.
Biomed Res Int. 2014;2014:203906. doi: 10.1155/2014/203906. Epub 2014 Nov 30.
Prostate cancer is the most common cancer diagnosis in American men, excluding skin cancer. The clinical behavior of prostate cancer varies from low-grade, slow growing tumors to high-grade aggressive tumors that may ultimately progress to metastases and cause death. Given the high incidence of men diagnosed with prostate cancer, conservative treatment strategies such as active surveillance are critical in the management of prostate cancer to reduce therapeutic complications of radiation therapy or radical prostatectomy. In this review, we will review the role of multiparametric MRI in the selection and follow-up of patients on active surveillance.
前列腺癌是美国男性中最常见的癌症诊断病例(不包括皮肤癌)。前列腺癌的临床行为各不相同,从低度、生长缓慢的肿瘤到高度侵袭性肿瘤,后者最终可能发展为转移并导致死亡。鉴于被诊断为前列腺癌的男性发病率很高,诸如主动监测等保守治疗策略在前列腺癌的管理中至关重要,以减少放射治疗或根治性前列腺切除术的治疗并发症。在本综述中,我们将回顾多参数磁共振成像在主动监测患者的选择和随访中的作用。