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他莫昔芬视网膜病变中的频域光学相干断层扫描成像技术

Spectral Domain OCT Imaging Techniques in Tamoxifen Retinopathy.

作者信息

Neuville Jessica, Yevseyenkov Vladimir

机构信息

*OD, FAAO †OD, PhD, FAAO Midwestern University, Arizona College of Optometry, Glendale, Arizona (both authors).

出版信息

Optom Vis Sci. 2015 Feb;92(2):e55-9. doi: 10.1097/OPX.0000000000000478.

Abstract

PURPOSE

To highlight the use of high-density spectral domain optical coherence tomography (SD-OCT) in the detection of tamoxifen retinopathy.

CASE REPORT

An 82-year-old asymptomatic woman with a history of tamoxifen therapy for breast cancer was found to have bilateral refractile retinal deposits on fundus examination. Detection on SD-OCT was compared across imaging techniques. High-density SD-OCT demonstrated hyperreflective deposits in the inner retinal layers of each eye consistent with the diagnosis of tamoxifen retinopathy.

CONCLUSIONS

The optimal SD-OCT scan technique depends on the ocular condition being imaged. High-density scan techniques require longer acquisition time but may enhance the detection of focal retinal pathology.

摘要

目的

强调高分辨率光谱域光学相干断层扫描(SD-OCT)在他莫昔芬视网膜病变检测中的应用。

病例报告

一名82岁无症状女性,有乳腺癌他莫昔芬治疗史,眼底检查发现双侧视网膜有可折射沉积物。比较了不同成像技术对其在SD-OCT上的检测情况。高分辨率SD-OCT显示每只眼视网膜内层有高反射性沉积物,符合他莫昔芬视网膜病变的诊断。

结论

最佳的SD-OCT扫描技术取决于所成像的眼部情况。高分辨率扫描技术需要更长的采集时间,但可能会提高对视网膜局灶性病变的检测能力。

相似文献

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Prevalence and Risk Factors of Tamoxifen Retinopathy.他莫昔芬视网膜病变的患病率及危险因素
Ophthalmology. 2020 Apr;127(4):555-557. doi: 10.1016/j.ophtha.2019.10.038. Epub 2019 Nov 7.

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