他莫昔芬视网膜病变的光学相干断层扫描结果
Optical coherence tomography findings in tamoxifen retinopathy.
作者信息
Gualino Vincent, Cohen Salomon Y, Delyfer Marie-Noëlle, Sahel José-Alain, Gaudric Alain
机构信息
Department of Ophthalmology, Hôpital Lariboisiĕre, Assistance Publique-Hôpitaux de Paris, Université Paris #7, Paris, France.
出版信息
Am J Ophthalmol. 2005 Oct;140(4):757-8. doi: 10.1016/j.ajo.2005.04.042.
PURPOSE
To describe optical coherence tomography (OCT) findings in two cases of typical tamoxifen retinopathy.
DESIGN
Observational cases report.
METHODS
Two patients with tamoxifen retinopathy were imaged with fluorescein angiography and OCT 3.
RESULTS
Fluorescein angiography showed foveolar hyperfluorescence. OCT revealed a foveolar cystoid space with focal disruption of the photoreceptor line. There was no evidence of macular edema or thickening.
CONCLUSIONS
In both cases, OCT findings are not consistent with previous descriptions of tamoxifen retinopathy, based on fundus examination and fluorescein angiography, which include a description of macular edema. This new imaging suggests that tamoxifen maculopathy may include a foveolar cystoid space different from macular edema.
目的
描述两例典型他莫昔芬视网膜病变的光学相干断层扫描（OCT）结果。
设计
观察性病例报告。
方法
对两名患有他莫昔芬视网膜病变的患者进行荧光素血管造影和OCT 3成像。
结果
荧光素血管造影显示黄斑中心凹高荧光。OCT显示黄斑中心凹囊样间隙，光感受器层有局灶性破坏。没有黄斑水肿或增厚的证据。
结论
在这两例病例中，基于眼底检查和荧光素血管造影，OCT结果与之前对他莫昔芬视网膜病变的描述不一致，之前的描述包括黄斑水肿。这种新的成像结果表明，他莫昔芬黄斑病变可能包括与黄斑水肿不同的黄斑中心凹囊样间隙。
Zotero 插件