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慢性阻塞性肺疾病患者6分钟踏阶试验的可重复性和敏感性

Reproducibility and Sensitivity of the 6-Minute Stepper Test in Patients with COPD.

作者信息

Coquart Jérémy B, Lemaître Frédéric, Castres Ingrid, Saison Sylvain, Bart Frédéric, Grosbois Jean-Marie

机构信息

a Université de Rouen, Faculté des Sciences du Sport et de l'Education Physique, Centre d'Etudes des Transformations des Activités Physiques et Sportives , Mont Saint Aignan , France.

d Formaction Santé , Perenchies , France.

出版信息

COPD. 2015;12(5):533-8. doi: 10.3109/15412555.2014.974733. Epub 2014 Dec 19.

DOI:10.3109/15412555.2014.974733
PMID:25526322
Abstract

The aims of this study were to test the reproducibility of the 6-minute stepper test (6MST), and evaluate its accuracy in detecting improved functional capacity after pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD). Thirty-five COPD outpatients performed two 6MSTs in the same session, before (6MST1 and 6MST2) and after (6MST3 and 6MST4) PR. The performance, perceived exertion, heart rate and arterial oxygen saturation were measured during each 6MST. The performance was higher during the second 6MST of the same session (before PR: 514 strokes during the 6MST2 > 471 strokes during the 6MST1, and after PR: 559 strokes during the 6MST4 > 508 strokes during the 6MST3; p = 0.04). After PR, 6MST performance was higher than before PR (6MST3 > 6MST1 and 6MST4 > 6MST2; P < 0.01). The bias (the difference in the number of strokes) between the two 6MSTs from the same session (before PR: 6MST2-6MST1 = 42 strokes vs after PR: 6MST4-6MST3 = 52 strokes) was not different (P = 0.34). However, both bias were greater than 0 (P < 0.001). The mean performances for the two 6MSTs of the same session (before PR: 6MST1 and 6MST2 and after PR: 6MST3 and 6MST4) were correlated with the bias between these performances (P < 0.01; r = 0.32). The perceived exertions were lower after PR (P < 0.02). The systematic improvement of performance (8-10%) during the second 6MST of the each session may be explained from the warming of hydraulic jacks of the stepper and/or learning effect. On the other hand, the 6MST seems sufficiently sensitive to detect functional capacity improvements after PR in patients with COPD.

摘要

本研究的目的是测试6分钟踏阶试验(6MST)的可重复性,并评估其在检测慢性阻塞性肺疾病(COPD)患者肺康复(PR)后功能能力改善方面的准确性。35例COPD门诊患者在同一时间段内进行了两次6MST,分别在PR前(6MST1和6MST2)和PR后(6MST3和6MST4)。在每次6MST期间测量运动表现、主观用力程度、心率和动脉血氧饱和度。同一时间段内第二次6MST的运动表现更高(PR前:6MST2期间514次踏阶>6MST1期间471次踏阶;PR后:6MST4期间559次踏阶>6MST3期间508次踏阶;p = 0.04)。PR后,6MST运动表现高于PR前(6MST3>6MST1且6MST4>6MST2;P < 0.01)。同一时间段内两次6MST之间的偏差(踏阶次数差异)(PR前:6MST2 - 6MST1 = 42次踏阶,PR后:6MST4 - 6MST3 = 52次踏阶)无差异(P = 0.34)。然而,两个偏差均大于0(P < 0.001)。同一时间段内两次6MST的平均运动表现(PR前:6MST1和6MST2,PR后:6MST3和6MST4)与这些运动表现之间的偏差相关(P < 0.01;r = 0.32)。PR后主观用力程度较低(P < 0.02)。每次6MST中第二次运动表现的系统性提高(8 - 10%)可能是由于踏阶器液压千斤顶的预热和/或学习效应。另一方面,6MST似乎对检测COPD患者PR后的功能能力改善足够敏感。

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