Yuksel Kemal, Goker Yasin Sakir, Yazici Ahmet Taylan, Ozkaya Abdullah, Cosar Gulen
From the Beyoglu Eye Training and Research Hospital, Istanbul (KY, YSG, ATY, AO); and Seydisehir Government Hospital, Ophthalmology Department, Konya, Turkey (GC).
Medicine (Baltimore). 2014 Dec;93(28):e182. doi: 10.1097/MD.0000000000000182.
To evaluate the effect of perifoveal pseudocysts on the anatomical outcomes of the idiopathic macular hole surgery as a prognostic factor. Twenty-one eyes of 20 consecutive patients with a Gass stage 3 or 4 idiopathic macular hole were enrolled in this prospective study between March 2012 and May 2013. Demographic data, medical history, and ocular examinations were recorded preoperatively and on postoperative day 1, week 1, and month 1, 3, and 6. Five spectral domain optical coherence tomography (SD-OCT) parameters were analyzed: macular hole (MH) basal diameter, MH minimum diameter, MH height, macular hole index, and a new parameter, the area of macular pseudocysts via the software of SD-OCT device at the widest cross section of the MH formation. The mean preoperative best-corrected visual acuity was 0.86±0.29 logarithm of the minimum angle of resolution (LogMAR) (between 0.4 and 1.3) and improved to 0.64±0.28 LogMAR (between 0.22 and 1.23) postoperatively (P=0.004). There was a statistical significant difference between both MH basal diameter and MH pseudocyst area with anatomical success, respectively (P=0.016 for MH basal diameter, P=0.004 for MH pseudocyst area). The anatomical closure was correlated with MH basal diameter and MH pseudocyst area (P=0.01 and P=0.001, respectively). Spearman correlation rank coefficient between with MH basal diameter and MH pseudocyst area was r=0.493 and statistically significant (P=0.02). Perifoveal pseudocysts seem to be associated with anatomic failure and may be used as a prognostic factor in MH surgery.
评估中心凹周围假性囊肿作为预后因素对特发性黄斑裂孔手术解剖学结果的影响。2012年3月至2013年5月期间，本前瞻性研究纳入了20例连续患者的21只患加斯3期或4期特发性黄斑裂孔的眼睛。术前及术后第1天、第1周、第1个月、第3个月和第6个月记录人口统计学数据、病史和眼部检查结果。分析了五个光谱域光学相干断层扫描（SD-OCT）参数：黄斑裂孔（MH）基底直径、MH最小直径、MH高度、黄斑裂孔指数，以及一个新参数，即通过SD-OCT设备软件在MH形成最宽横截面处测量的黄斑假性囊肿面积。术前平均最佳矫正视力为0.86±0.29最小分辨角对数（LogMAR）（范围在0.4至1.3之间），术后提高至0.64±0.28 LogMAR（范围在0.22至1.23之间）（P = 0.004）。MH基底直径和MH假性囊肿面积与解剖学成功之间分别存在统计学显著差异（MH基底直径P = 0.016，MH假性囊肿面积P = 0.004）。解剖学闭合与MH基底直径和MH假性囊肿面积相关（分别为P = 0.01和P = 0.001）。MH基底直径与MH假性囊肿面积之间的Spearman相关秩系数为r = 0.493，具有统计学意义（P = 0.02）。中心凹周围假性囊肿似乎与解剖学失败有关，可能作为MH手术的预后因素。
