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天然存在的 2-(2-苯乙基)色酮,结构鉴定和生物活性。

Natural occurring 2-(2-phenylethyl) chromones, structure elucidation and biological activities.

机构信息

a Department of Pharmacognosy and Pharmaceutical Chemistry , Faculty of Pharmacy, Taibah University, Al Madinah Al , Munawwarah 30078 , Kingdom of Saudi Arabia.

出版信息

Nat Prod Res. 2015;29(16):1489-520. doi: 10.1080/14786419.2014.991323. Epub 2014 Dec 20.

Abstract

2-(2-Phenylethyl) chromone (PEC), an uncommon class of chromones, possesses a phenylethyl substituent at the C2 position. They have been isolated from a few plant species. They have promising biological activities such as neuro-protective, cytotoxic, acetylcholinesterase inhibitory, antibacterial and anti-inflammatory. This review focuses on the naturally occurring PEC derivatives, their sources, physical and spectral data, as well as biological activities.

摘要

2-(2-苯乙基)色酮(PEC)是一类罕见的色酮,其 C2 位具有苯乙基取代基。它们已从少数几种植物中分离出来。它们具有有前途的生物活性,如神经保护、细胞毒性、乙酰胆碱酯酶抑制、抗菌和抗炎作用。本综述重点介绍了天然存在的 PEC 衍生物,它们的来源、物理和光谱数据以及生物活性。

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