Khalid Laila, Liebschutz Jane M, Xuan Ziming, Dossabhoy Shernaz, Kim Yoona, Crooks Denise, Shanahan Christopher, Lange Allison, Heymann Orlaith, Lasser Karen E
Section of General Internal Medicine, Boston Medical Center, School of Medicine, Boston University, Boston, Massachusetts, USA.
Pain Med. 2015 Mar;16(3):480-7. doi: 10.1111/pme.12602. Epub 2014 Dec 19.
The aim of this study was to compare adherence to opioid prescribing guidelines and potential opioid misuse in patients of resident vs attending physicians.
Retrospective cross-sectional study.
Large primary care practice at a safety net hospital in New England.
Patients 18-89 years old, with at least one visit to the primary care clinic within the past year and were prescribed long-term opioid treatment for chronic noncancer pain.
Data were abstracted from the electronic medical record by a trained data analyst through a clinical data warehouse. The primary outcomes were adherence to any one of two American Pain Society Guidelines: (1) documentation of at least one opioid agreement (contract) ever and (2) any urine drug testing in the past year, and evidence of potential prescription misuse defined as ≥2 early refills. We employed logistic regression analysis to assess whether patients' physician status predicts guideline adherence and/or potential opioid misuse.
Similar proportions of resident and attending patients had a controlled substance agreement (45.1% of resident patients vs. 42.4% of attending patient, P = 0.47) or urine drug testing (58.6% of resident patients vs. 63.6% of attending patients, P = 0.16). Resident patients were more likely to have two or more early refills in the past year relative to attending patients (42.8% vs. 32.5%; P = 0.004). In the adjusted regression analysis, resident patients were more likely to receive early refills (odds ratio 1.82, 95% confidence interval 1.26-2.62) than attending patients.
With some variability, residents and attending physicians were only partly compliant with national guidelines. Residents were more likely to manage patients with a higher likelihood of opioid misuse.
本研究旨在比较住院医师和主治医师的患者对阿片类药物处方指南的遵循情况以及潜在的阿片类药物滥用情况。
回顾性横断面研究。
新英格兰一家安全网医院的大型初级保健机构。
年龄在18 - 89岁之间,过去一年至少到初级保健诊所就诊一次且因慢性非癌性疼痛接受长期阿片类药物治疗的患者。
经过培训的数据分析师通过临床数据仓库从电子病历中提取数据。主要结局指标为是否遵循美国疼痛学会两项指南中的任意一项:(1)曾记录至少一份阿片类药物协议(合同);(2)过去一年进行过任何尿液药物检测,以及潜在处方滥用的证据,定义为提前≥2次续方。我们采用逻辑回归分析来评估患者的医师类型是否能预测指南遵循情况和/或潜在的阿片类药物滥用。
住院医师和主治医师的患者中,签订管制药品协议的比例相似(住院医师患者为45.1%,主治医师患者为42.4%,P = 0.47),或进行尿液药物检测的比例相似(住院医师患者为58.6%,主治医师患者为63.6%,P = 0.16)。与主治医师的患者相比,住院医师的患者在过去一年更有可能提前2次或更多次续方(42.8%对32.5%;P = 0.004)。在调整后的回归分析中,住院医师的患者比主治医师的患者更有可能提前续方(比值比1.82,95%置信区间1.26 - 2.62)。
尽管存在一些差异,但住院医师和主治医师仅部分符合国家指南。住院医师更有可能管理阿片类药物滥用可能性较高的患者。