Adrian T, Schlipköter U, Roggendorf M, Wigand R
Abteilung für Virologie, Universitätskliniken, Homburg/Saar.
Zentralbl Bakteriol. 1989 Sep;271(3):339-44. doi: 10.1016/s0934-8840(89)80032-5.
A unique genome type of adenovirus 5 was isolated from 37 specimens of 25 patients. DNA restriction analysis was performed with seven endonucleases. Part of the patients were treated at a bone marrow transplantation unit in Munich. Nosocomial spread, rather than activation of endogenous adenovirus infection, was likely for many of them. In addition, sporadic cases suggested an endemicity of this genome type in Bavaria.
从25名患者的37份样本中分离出了一种独特的腺病毒5型基因组。使用七种核酸内切酶进行了DNA限制性分析。部分患者在慕尼黑的一个骨髓移植单位接受治疗。对他们中的许多人来说,可能是医院内传播,而非内源性腺病毒感染的激活。此外,散发病例表明这种基因组类型在巴伐利亚存在地方性流行。