Magalhães Gabriella Fernandes, Santos Gláucia Noblat de Carvalho, Rosa Mário Borges, Noblat Lúcia de Araújo Costa Beisl
Multidisciplinary Comprehensive Health Residency in adult health care focused on cardiovascular care at Professor Edgard Santos University Hospital, Federal University of Bahia State (UFBA), Salvador, Bahia, Brazil.
Professor Edgard Santos University Hospital, Federal University of Bahia State (UFBA), Salvador, Bahia Brazil.
PLoS One. 2014 Dec 22;9(12):e115491. doi: 10.1371/journal.pone.0115491. eCollection 2014.
To compare drugs prescribed on hospital admission with the list of drugs taken prior to admission for adult patients admitted to a cardiology unit and to identify the role of a pharmacist in identifying and resolving medication discrepancies.
This study was conducted in a 300 bed university hospital in Brazil. Clinical pharmacists taking medication histories and reconciling medications prescribed on admission with a list of drugs used prior to admission. Discrepancies were classified as justified (e.g., based on the pharmacotherapeutic guidelines of the hospital studied) or unintentional. Treatments were reviewed within 48 hours following hospitalization. Unintentional discrepancies were further classified according to the categorization of medication error severity. Pharmacists verbally contacted the prescriber to recommend actions to resolve the discrepancies.
A total of 181 discrepancies were found in 50 patients (86%). Of these discrepancies, 149 (82.3%) were justified changes to the patient's home medication regimen; however, 32 (17.7%) discrepancies found in 24 patients were unintentional. Pharmacists made 31 interventions and 23 (74.2%) were accepted. Among unintentional discrepancies, the most common was a different medication dose on admission (42%). Of the unintentional discrepancies 13 (40.6%) were classified as error without harm, 11 (34.4%) were classified as error without harm but which could affect the patient and require monitoring, 3 (9.4%) as errors could have resulted in harm and 5 (15.6%) were classified as circumstances or events that have the capacity to cause harm.
The results revealed a high number of unintentional discrepancies and the pharmacist can play an important role by intervening and correcting medication errors at a hospital cardiology unit.
比较心内科成年住院患者入院时所开药物与入院前服用药物清单,并确定药剂师在识别和解决用药差异方面的作用。
本研究在巴西一家拥有300张床位的大学医院进行。临床药剂师记录用药史,并将入院时所开药物与入院前使用的药物清单进行核对。差异被分类为合理的(例如,基于所研究医院的药物治疗指南)或无意的。在住院后48小时内对治疗进行审查。无意的差异根据用药错误严重程度分类进一步分类。药剂师通过口头联系开处方者,建议采取措施解决差异。
50名患者(86%)共发现181处差异。在这些差异中,149处(82.3%)是对患者家庭用药方案的合理调整;然而,在24名患者中发现的32处(17.7%)差异是无意的。药剂师进行了31次干预,其中23次(74.2%)被接受。在无意的差异中,最常见的是入院时药物剂量不同(42%)。在无意的差异中,13处(40.6%)被分类为无伤害错误,11处(34.4%)被分类为无伤害但可能影响患者并需要监测的错误,3处(9.4%)为可能导致伤害的错误,5处(15.6%)被分类为有造成伤害能力的情况或事件。
结果显示无意差异数量较多,药剂师通过在医院心内科进行干预和纠正用药错误可发挥重要作用。