亚洲竹叶青属（Trimeresurus属）毒蛇毒液的酶学性质和毒性特性的比较研究。

A comparative study of the enzymatic and toxic properties of venoms of the Asian lance-headed pit viper (Genus Trimeresurus).

Tan N H, Armugam A, Tan C S

Department of Biochemistry, University of Malaya, Kuala Lumpur, Malaysia.

Comp Biochem Physiol B. 1989;93(4):757-62. doi: 10.1016/0305-0491(89)90042-4.

Abstract

The lethalities, anticoagulant effects, hermorrhagic, thrombin-like enzyme, hyaluronidase, protease, arginine ester hydrolase, 5'-nucleotidase, L-amino acid oxidase, alkaline phosphomonoesterase, phosphodiesterase and phospholipase A activities of twenty-three samples of venoms from twelve species of Asian lance-headed pit vipers (genus Trimeresurus) were examined. 2. The results indicate that notwithstanding individual variations in venom properties, the differences in biological properties of the Trimeresurus venoms can be used for the differentiation of venoms from different species of Trimeresurus. 3. The results also suggest that differences in the biological properties of snake venoms are useful parameters in the classification of snake species. 4. Our results indicate that venoms from the species T. okinavensis exhibited biological properties markedly different from other Trimeresurus venoms examined. This observation supports the recently proposed reclassification of T. okinavensis as a member of the genus Ovophis, rather than the genus Trimeresurus.

摘要

检测了12种亚洲蝮属（竹叶青属）蝰蛇的23个毒液样本的致死率、抗凝作用、出血性、类凝血酶、透明质酸酶、蛋白酶、精氨酸酯水解酶、5'-核苷酸酶、L-氨基酸氧化酶、碱性磷酸单酯酶、磷酸二酯酶和磷脂酶A的活性。2. 结果表明，尽管毒液特性存在个体差异，但竹叶青属蛇毒的生物学特性差异可用于区分不同种类竹叶青属的毒液。3. 结果还表明，蛇毒生物学特性的差异是蛇类分类的有用参数。4. 我们的结果表明，冲绳竹叶青蛇的毒液表现出与所检测的其他竹叶青属毒液明显不同的生物学特性。这一观察结果支持了最近提出的将冲绳竹叶青蛇重新分类为卵蝰属成员，而非竹叶青属的提议。