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儿童注意缺陷/多动障碍药物治疗与龋齿

Attention deficit/hyperactivity disorder medication and dental caries in children.

作者信息

Rosenberg Sandra S, Kumar Sajeesh, Williams Nancy J

出版信息

J Dent Hyg. 2014 Dec;88(6):342-7.

Abstract

PURPOSE

Few studies have been conducted to investigate the effects, if any, of specific medication used to manage the symptoms of attention deficit/hyperactivity disorder (ADHD) as a risk factor for dental caries. A reported side-effect of the medication is a reduction in saliva. Healthy saliva has been shown to play many important functions in the prevention of dental caries. The focus of this review is to determine if any evidence exists to confirm that stimulant medication used to treat the symptoms of ADHD in children increases the risk of dental caries by virtue of its effect on the reduction of salivary flow.

METHODS

A MEDLINE search was conducted for relevant studies. Search terms used were dental caries, attention deficit/hyperactivity disorder, ADHD, pharmacologic treatment of ADHD, stimulant medication, xerostomia, dry-mouth and saliva flow. Publication dates ranged from 2002 to 2012.

RESULTS

Although dental caries prevalence has been found to be higher in children with ADHD, decreased salivary flow as a side-effect of pharmacological treatment does not appear to be responsible.

CONCLUSION

Dental caries is a multi-factorial disease process. The most effective method of reducing dental caries in ADHD children is more frequent recare visits focusing on home plaque removal practices along with dietary counseling to reduce the consumption of cariogenic foods and drinks. This can only be accomplished with inclusion of the parent/guardian in the process.

摘要

目的

很少有研究调查用于治疗注意力缺陷/多动障碍(ADHD)症状的特定药物作为龋齿风险因素的影响(如果有)。该药物的一个报道副作用是唾液分泌减少。健康的唾液已被证明在预防龋齿中发挥许多重要作用。本综述的重点是确定是否有证据证实用于治疗儿童ADHD症状的刺激性药物因其对唾液分泌减少的影响而增加龋齿风险。

方法

对相关研究进行了MEDLINE检索。使用的检索词为龋齿、注意力缺陷/多动障碍、ADHD、ADHD的药物治疗、刺激性药物、口干症、口干和唾液流量。出版日期范围为2002年至2012年。

结果

尽管已发现ADHD儿童的龋齿患病率较高,但药物治疗的副作用唾液分泌减少似乎不是原因。

结论

龋齿是一个多因素的疾病过程。降低ADHD儿童龋齿的最有效方法是更频繁地复诊,重点是家庭菌斑清除措施以及饮食咨询,以减少致龋食物和饮料的摄入。这只有在家长/监护人参与该过程的情况下才能实现。

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