一名最初外观健康的早产儿发生宫内单纯疱疹病毒上行感染。
Ascending in utero herpes simplex virus infection in an initially healthy-appearing premature infant.
作者信息
Edwards Morven S, Popek Edwina J, Wise Brittany, Hatzenbuehler Lindsay, Arunachalam Athis R, Hair Amy B
机构信息
1 Section of Infectious Disease, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA.
出版信息
Pediatr Dev Pathol. 2015 Mar-Apr;18(2):155-8. doi: 10.2350/14-09-1548-CR.1. Epub 2014 Dec 23.
The usual route of acquisition for intrauterine herpes simplex virus (HSV) infection is transplacental. We evaluated a premature infant with in utero acquisition of HSV resulting from ascending infection. Histopathologic evidence of chronic chorioamnionitis and positive staining with immunohistochemistry for HSV in the placenta and umbilical cord established the diagnosis. The clinical presentation was also of interest in that the infant was initially healthy appearing.
宫内单纯疱疹病毒（HSV）感染的常见获得途径是经胎盘传播。我们评估了一名因上行感染而在子宫内获得HSV的早产儿。胎盘和脐带中慢性绒毛膜羊膜炎的组织病理学证据以及HSV免疫组织化学染色阳性确立了诊断。该婴儿最初外观健康，其临床表现也很有意思。
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