Pinninti Swetha G, Kimberlin David W
Division of Pediatric Infectious Diseases, The University of Alabama at Birmingham, 1600 Seventh Avenue South, CHB 308, Birmingham, AL 35233, USA.
Division of Pediatric Infectious Diseases, The University of Alabama at Birmingham, 1600 Seventh Avenue South, CHB 303, Birmingham, AL 35233, USA.
Clin Perinatol. 2014 Dec;41(4):945-55. doi: 10.1016/j.clp.2014.08.012. Epub 2014 Sep 27.
Genital herpes simplex virus (HSV) infections are very common worldwide. Approximately 22% of pregnant women are infected genitally with HSV, and most of them are unaware of this. The most devastating consequence of maternal genital herpes is HSV disease in the newborn. Although neonatal HSV infections remain uncommon, due to the significant morbidity and mortality associated with the infection, HSV infection in the newborn is often considered in the differential diagnosis of ill neonates. This review summarizes the epidemiology and management of neonatal HSV infections and discusses strategies to prevent HSV infection in the newborn.
生殖器单纯疱疹病毒（HSV）感染在全球范围内非常普遍。约22%的孕妇生殖器感染了HSV，其中大多数人并未意识到这一点。孕产妇生殖器疱疹最严重的后果是新生儿感染HSV疾病。虽然新生儿HSV感染仍然不常见，但由于该感染会导致严重的发病率和死亡率，新生儿HSV感染常被纳入患病新生儿的鉴别诊断中。本综述总结了新生儿HSV感染的流行病学和管理方法，并讨论了预防新生儿HSV感染的策略。
