Turk J Med Sci. 2014;44(2):295-304.
To investigate the effects of a magnetic field (MF) on febrile seizure latency, seizure duration, and electroencephalographic (EEG) recordings in a rat febrile convulsion model.
Thirty-six rats were randomly allocated into 1 of 6 groups: sham group (S), febrile convulsion (FC) group without MF exposure, MF group without FC, group exposed to MF before FC (MF + FC), group exposed to MF after FC (FC + MF), and group exposed to MF before and after FC (MF + FC + MF). The rectal temperature after febrile seizure induction, seizure latency, seizure duration, and EEG recordings were recorded for all animals.
Repeated hyperthermic exposure decreased the seizure latency and duration. The effect of the MF was more prominent on seizure duration than on latencies. MF exposure for 10 or 12 days increased seizure latency. MF exposure increased the pathologic theta and delta waves and decreased the beta waves, which are frequently seen in awake animals.
Our results suggest that MF exposure has a negative effect on brain waves, and this effect becomes more evident with prolonged exposure. On the other hand, MF exposure significantly decreased the convulsion durations.
研究磁场（MF）对发热性惊厥潜伏期、发作持续时间和脑电图（EEG）记录的影响，建立大鼠发热性惊厥模型。
将 36 只大鼠随机分为 6 组：假手术组（S）、无 MF 暴露的发热性惊厥（FC）组、MF 组、FC 前暴露 MF 组（MF + FC）、FC 后暴露 MF 组（FC + MF）和 MF 前后暴露组（MF + FC + MF）。记录所有动物发热性惊厥诱导后的直肠温度、发作潜伏期、发作持续时间和 EEG 记录。
反复高热暴露会降低发作潜伏期和持续时间。MF 的作用对发作持续时间的影响比对潜伏期的影响更为明显。MF 暴露 10 或 12 天会增加发作潜伏期。MF 暴露增加了病理θ波和δ波，并减少了β波，这在清醒动物中经常出现。
我们的结果表明，MF 暴露对脑电波有负面影响，随着暴露时间的延长，这种影响变得更加明显。另一方面，MF 暴露显著缩短了惊厥持续时间。
