[从感染艾滋病毒儿童中分离出的葡萄球菌的结构和生物学特性]
[Characteristics of structure and biological properties of staphylococci isolated from children with HIV-infection].
作者信息
Zakharova Iu V
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 2014 Sep-Oct(5):3-7.
AIM
Study species composition and factors of pathogenicity of staphylococci isolated from intestine biotope of children with HIV-infection.
MATERIALS AND METHODS
75 strains of staphylococci from HIV-positive and 45 strains from HIV-negatfive children were isolated and identified. Factors of specific adhesion, colonization potential, invasion factors and toxin-formation of staphylococci were studied.
RESULTS
In HIV-infected children Staphylococcus aureus, Staphylococcus xylosus, Staphylococcus epidermidis dominated. Quantitative level of S. aureus was 1.8 x 10(7) PFU/g. Adhesion, production of hemolysin, DNAse did not differ from the comparison group (p > 0.05). Lipase activity in staphylococci from HIV-infected children was higher than in the control group (p < 0.05).
CONCLUSION
The data obtained reveal some mechanisms of development of endogenous infection in HIV-infected children.
目的
研究从感染艾滋病毒儿童的肠道生境中分离出的葡萄球菌的种类组成和致病因素。
材料与方法
分离并鉴定了75株来自艾滋病毒阳性儿童的葡萄球菌菌株和45株来自艾滋病毒阴性儿童的葡萄球菌菌株。研究了葡萄球菌的特异性黏附因子、定植潜力、侵袭因子和毒素形成。
结果
在感染艾滋病毒的儿童中，金黄色葡萄球菌、木糖葡萄球菌、表皮葡萄球菌占主导。金黄色葡萄球菌的定量水平为1.8×10⁷CFU/g。黏附、溶血素产生、DNA酶与对照组无差异（p>0.05）。感染艾滋病毒儿童的葡萄球菌中的脂肪酶活性高于对照组（p<0.05）。
结论
所获得的数据揭示了感染艾滋病毒儿童内源性感染发展的一些机制。
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