Department of Mechanical & Aerospace Engineering, Princeton University, Princeton, NJ 08544, USA.
Lab Chip. 2015 Feb 21;15(4):1110-5. doi: 10.1039/c4lc01347f.
We study pressure and flow-rate fluctuations in microchannels, where the flow rate is supplied by a syringe pump. We demonstrate that the pressure fluctuations are induced by the flow-rate fluctuations coming from mechanical oscillations of the pump motor. Also, we provide a mathematical model of the effect of the frequency of the pump on the normalized amplitude of pressure fluctuations and introduce a dimensionless parameter incorporating pump frequency, channel geometry and mechanical properties that can be used to predict the performance of different microfluidic device configurations. The normalized amplitude of pressure fluctuations decreases as the frequency of the pump increases and the elasticity of the channel material decreases. The mathematical model is verified experimentally over a range of typical operating conditions and possible applications are discussed.
我们研究了注射器泵提供流量的微通道中的压力和流量波动。我们证明压力波动是由泵电机机械振动引起的流量波动引起的。此外，我们还提供了一个数学模型，用于描述泵频率对压力波动归一化幅度的影响，并引入了一个包含泵频率、通道几何形状和机械性能的无量纲参数，可用于预测不同微流控器件配置的性能。压力波动的归一化幅度随着泵频率的增加和通道材料的弹性的降低而减小。该数学模型在一系列典型工作条件下进行了实验验证，并讨论了可能的应用。
