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社区获得性肺炎细菌学特征及死亡率趋势的变化

Changing bacteriological profile and mortality trends in community acquired pneumonia.

作者信息

Khadanga Sagar, Karuna Tadepalli, Thatoi Pravat Kumar, Behera Sarat Kumar

机构信息

Department of Medicine, LN Medical College and JK Hospital, Bhopal, Madhya Pradesh, India.

Department of Microbiology, All India Institute of Medical Science, Bhopal, Madhya Pradesh, India.

出版信息

J Glob Infect Dis. 2014 Oct;6(4):186-8. doi: 10.4103/0974-777X.145251.

Abstract

There are very few and conflicting Indian data regarding the bacteriological etiology of community acquired pneumonia (CAP). Adding to this agony, there is no credible data from the eastern part of India. This is a cross-sectional study and descriptive in nature over a period of 1-year. Of the 464 cases of the study population, we could isolate aerobic bacteria in 149 patients (32.1%). Streptococcus pneumoniae has been identified as the most common organism causing CAP (68/149). Gram-negative bacilli (GNB) as a group exceeded marginally over S. pneumoniae (69/149). Among GNB, Pseudomonas aeruginosa was the most common organism (31/69), followed by Klebsiella pneumoniae (29/69). Staphylococcus aureus was identified in (12/149) cases. Co-amoxyclav is still the most sensitive drug for S. pneumoniae. P. aeruginosa was most sensitive to imipenam followed by piperacillin-tazobactam.

摘要

关于社区获得性肺炎(CAP)的细菌学病因,印度的数据非常少且相互矛盾。更糟糕的是,印度东部没有可靠的数据。这是一项为期1年的横断面描述性研究。在464例研究人群中,我们在149例患者(32.1%)中分离出需氧菌。肺炎链球菌已被确定为引起CAP的最常见病原体(68/149)。革兰氏阴性杆菌(GNB)作为一个群体略超过肺炎链球菌(69/149)。在GNB中,铜绿假单胞菌是最常见的病原体(31/69),其次是肺炎克雷伯菌(29/69)。在(12/149)例病例中鉴定出金黄色葡萄球菌。阿莫西林克拉维酸仍然是对肺炎链球菌最敏感的药物。铜绿假单胞菌对亚胺培南最敏感,其次是哌拉西林他唑巴坦。

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