埃塞俄比亚儿童肺炎康复率及其预测因素：系统评价与荟萃分析

Recovery Rate of Children From Pneumonia and Its Predictors in Ethiopia: A Systematic Review and Meta-Analysis.

作者信息

Wondmeneh Temesgen Gebeyehu, Hadato Abduhakm Hara

机构信息

Department of Public Health, College of Medical and Health Science Samara University Semera Afar Ethiopia.

出版信息

Health Sci Rep. 2025 Sep 1;8(9):e71127. doi: 10.1002/hsr2.71127. eCollection 2025 Sep.

DOI:10.1002/hsr2.71127

PMID:40900683

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12399988/

Abstract

BACKGROUND

Sub-Saharan Africa accounts for the majority of child pneumonia mortality and morbidity. The pooled recovery rate of children from pneumonia and its predictors is not well known in Ethiopia.

AIM

The aim of this systematic review and meta-analysis is to determine the pooled recovery rate of children from pneumonia and its predictors in Ethiopia.

METHODS

The major databases used to search articles were Web of Science, Science Direct, PubMed, Google Scholar, and African journals online. The data were extracted independently from eligible primary studies using a standardized spreadsheet. The quality of the included studies was assessed using the Newcastle-Ottawa scale critical appraisal checklist for the cohort study. The pooled effect size with a 95% CI was estimated by the random-effects model of meta-analysis. The amount of heterogeneity across the studies was assessed by . A sensitivity analysis was conducted.

RESULTS

In this systematic review and meta-analysis, 6173 children with pneumonia were included; out of these, 4871 had recovered. The pooled recovery rate of children from pneumonia was 17.7 (95% CI: 14.61-20.79) per 100 children per day. Children who lived in rural areas (AHR = 0.81, 95% CI: 0.74-0.88), stunted children (AHR = 0.77, 95% CI: 0.56-0.99), children with dangerous signs (AHR = 0.78, 95% CI: 0.66-0.9), not fully vaccinated children (AHR = 0.55, 95% CI: 0.11-0.99), comorbid children (AHR = 0.57, 95% CI: 0.48-0.65), and children with a history of respiratory infection (AHR = 0.86, 95% CI: 0.76-0.96) had a lower recovery rate from pneumonia.

CONCLUSION

In the current study, the recovery rate of children from pneumonia was 17.7 per 100 child-days. Children living in rural areas recovered more slowly. Healthcare providers should give special attention at admission for screening of children with stunted, danger signs, not fully vaccinated, comorbid, and histories of respiratory tract infection.

摘要

背景

撒哈拉以南非洲地区儿童肺炎死亡率和发病率占多数。在埃塞俄比亚，儿童肺炎的综合康复率及其预测因素尚不为人所知。

目的

本系统评价和荟萃分析的目的是确定埃塞俄比亚儿童肺炎的综合康复率及其预测因素。

方法

用于检索文章的主要数据库有科学网、科学Direct、PubMed、谷歌学术和非洲在线期刊。使用标准化电子表格从符合条件的原始研究中独立提取数据。使用队列研究的纽卡斯尔-渥太华量表关键评价清单评估纳入研究的质量。通过荟萃分析的随机效应模型估计95%置信区间的合并效应量。通过评估各研究间的异质性程度。进行了敏感性分析。

结果

在本系统评价和荟萃分析中，纳入了6173例肺炎儿童；其中，4871例已康复。儿童肺炎的综合康复率为每100名儿童每天17.7例（95%置信区间：14.61 - 20.79）。生活在农村地区的儿童（调整后风险比[AHR]=0.81，95%置信区间：0.74 - 0.88）、发育迟缓儿童（AHR = 0.77，95%置信区间：0.56 - 0.99）、有危险体征的儿童（AHR = 0.78，95%置信区间：0.66 - 0.9）、未完全接种疫苗的儿童（AHR = 0.55，95%置信区间：0.11 - 0.99）、患有合并症的儿童（AHR = 0.57，95%置信区间：0.48 - 0.65）以及有呼吸道感染史的儿童（AHR = 0.86，95%置信区间：0.76 - 0.96）肺炎康复率较低。