Cochrane Metabolic and Endocrine Disorders Review Group, Institute of General Practice, Medical Faculty of the Heinrich-Heine University, Düsseldorf, Germany.
Library, Medical Faculty of Mannheim, University of Heidelberg.
Transfus Med Hemother. 2014 Oct;41(5):364-74. doi: 10.1159/000366179. Epub 2014 Sep 15.
To be able to take well-informed decisions or carry out sound research, clinicians and researchers alike require specific information seeking skills matching their respective information needs. Biomedical information is traditionally available via different literature databases. This article gives an introduction to two diverging sources, PubMed (23 million references) and The Cochrane Library (800,000 references), both of which offer sophisticated instruments for searching an increasing amount of medical publications of varied quality and ambition. Whereas PubMed as an unfiltered source of primary literature comprises all different kinds of publication types occurring in academic journals, The Cochrane Library is a pre-filtered source which offers access to either synthesized publication types or critically appraised and carefully selected references. A search approach has to be carried out deliberately and requires a good knowledge on the scope and features of the databases as well as on the ability to build a search strategy in a structured way. We present a specific and a sensitive search approach, making use of both databases within two application case scenarios in order to identify the evidence on granulocyte transfusions for infections in adult patients with neutropenia.
为了能够做出明智的决策或开展可靠的研究，临床医生和研究人员都需要具备与其各自信息需求相匹配的特定信息搜索技能。生物医学信息传统上可通过不同的文献数据库获得。本文将介绍两个不同的来源，PubMed（2300 万条参考文献）和 The Cochrane Library（80 万条参考文献），它们都提供了复杂的工具来搜索数量不断增加的各种质量和目标的医学出版物。虽然作为原始文献的未筛选来源，PubMed 包含学术期刊中出现的所有不同类型的出版物，但 Cochrane Library 是一个预先筛选的来源，可访问综合出版类型或经过批判性评估和精心选择的参考文献。搜索方法必须经过深思熟虑，需要对数据库的范围和特点以及以结构化方式构建搜索策略的能力有很好的了解。我们展示了一种具体而敏感的搜索方法，在两个应用案例场景中同时使用这两个数据库，以确定粒细胞输注治疗中性粒细胞减少症成年患者感染的证据。
