植物代谢产物。来自毛钩藤和阔叶鱼骨木的奎诺酸糖苷的结构及体外抗病毒活性。

Plant metabolites. Structure and in vitro antiviral activity of quinovic acid glycosides from Uncaria tomentosa and Guettarda platypoda.

作者信息

Aquino R, De Simone F, Pizza C, Conti C, Stein M L

机构信息

Dipartimento di Chimica delle Sostanze Naturali, Universitá di Napoli, Italy.

出版信息

J Nat Prod. 1989 Jul-Aug;52(4):679-85. doi: 10.1021/np50064a002.

DOI:10.1021/np50064a002

PMID:2553871

Abstract

A reinvestigation of the bark of Uncaria tomentosa afforded, in addition to the major quinovic acid glycosides 1-3, three further glycosides 4-6. The structures were elucidated by spectral and chemical studies. Furthermore, a series of antiviral tests were performed on all these glycosides and on the related glycosides 7-9, previously isolated from Guettarda platypoda.

摘要

对毛钩藤树皮进行的再研究，除了得到主要的奎诺维酸糖苷1 - 3外，还得到了另外三种糖苷4 - 6。通过光谱和化学研究阐明了其结构。此外，对所有这些糖苷以及先前从光叶巴戟中分离得到的相关糖苷7 - 9进行了一系列抗病毒试验。