Schecker Michael, Kochler Carsten, Schmidtke Klaus, Rauh Reinhold
Neurolinguistisches Labor NLL, Klinik für Psychiatrie, Psychotherapie und Psychosomatik im Kindes- und Jugendalter, Universität Freiburg, Freiburg, Germany.
Klinik für Hirnleistungsstörungen Klausenbach, Nordrach, Universität Freiburg, Freiburg, Germany.
Dement Geriatr Cogn Dis Extra. 2014 Nov 12;4(3):442-9. doi: 10.1159/000368317. eCollection 2014 Sep.
Speech disorders already occur in the early phases of Alzheimer's disease (AD). As a possible cause, problems of executive processes are discussed. Cognitive slowing is also repeatedly addressed.
Are there any connections between cognitive slowing and speech disorders in AD? And is there a relationship between cognitive slowing and executive processes?
The data of 72 healthy controls and 52 AD patients were examined with regard to their language performance and their response times in a computerized Stroop paradigm.
The AD patients showed significantly worse results in all language tests as well as much longer reaction times in all Stroop conditions, especially in the interference condition (Stroop 3). Speech errors and response times correlated with severity (MMSE), and the speech errors correlated with the reaction times in Stroop 3 (interference condition, which reflects the processing time of executive processes).
The most interesting question now is: How are language processing and executive processing time (Stroop 3) related?
言语障碍在阿尔茨海默病（AD）的早期阶段就已出现。作为一种可能的原因，人们讨论了执行过程的问题。认知减慢也被反复提及。
AD患者的认知减慢与言语障碍之间是否存在联系？认知减慢与执行过程之间是否存在关系？
对72名健康对照者和52名AD患者的数据进行了检查，涉及他们在计算机化斯特鲁普范式中的语言表现和反应时间。
AD患者在所有语言测试中的结果明显更差，并且在所有斯特鲁普条件下的反应时间都长得多，尤其是在干扰条件下（斯特鲁普3）。言语错误和反应时间与严重程度（MMSE）相关，言语错误与斯特鲁普3中的反应时间相关（干扰条件，反映执行过程的处理时间）。
现在最有趣的问题是：语言处理与执行处理时间（斯特鲁普3）是如何相关的？
