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静磁场对4.9兆电子伏质子和23兆电子伏α粒子诱发染色体畸变的影响。

Effect of static magnetic field on the induction of chromosome aberrations by 4.9 MeV protons and 23 MeV alpha particles.

作者信息

Takatsuji T, Sasaki M S, Takekoshi H

出版信息

J Radiat Res. 1989 Sep;30(3):238-46. doi: 10.1269/jrr.30.238.

Abstract

The effect of static magnetic field applied during in vitro exposure to 4.9 MeV protons and 23 MeV alpha particles on the induction of chromosome aberrations in human peripheral blood lymphocytes was studied. The mean frequency of dicentrics in cells irradiated in magnetic field of a magnitude about one Tesla tended to be higher than that irradiated in the absence of magnetic field for both protons and alpha particles, and the analysis of dose-effect relationships indicated that for protons the magnetic field significantly affected the dose-effect relationship. The intercellular distribution of chromosome aberrations, one of the measures of radiation quality, was not significantly influenced by the magnetic field.

摘要

研究了体外暴露于4.9兆电子伏特质子和23兆电子伏特α粒子期间施加静磁场对人外周血淋巴细胞染色体畸变诱导的影响。对于质子和α粒子,在强度约为1特斯拉的磁场中辐照的细胞中双着丝粒的平均频率往往高于无磁场辐照的细胞,剂量效应关系分析表明,对于质子,磁场显著影响剂量效应关系。作为辐射质量指标之一的染色体畸变的细胞间分布未受到磁场的显著影响。

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