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具有群体感应活性的嗜水气单胞菌187菌株的全基因组分析

Whole-Genome Analysis of Aeromonas hydrophila Strain 187, Exhibiting Quorum-Sensing Activity.

作者信息

Chan Xin-Yue, Chua Kek Heng, Yin Wai-Fong, Puthucheary S D, Chan Kok-Gan

机构信息

Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.

Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Genome Announc. 2014 Dec 24;2(6):e01360-14. doi: 10.1128/genomeA.01360-14.

DOI:10.1128/genomeA.01360-14

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4276835/

Abstract

Aeromonas hydrophila is a quorum-sensing (QS) bacterium that causes diarrhea in humans upon infection. Here, we report the genome of pathogenic Aeromonas hydrophila strain 187, which possesses a QS gene responsible for signaling molecule N-acyl homoserine lactone (AHL) synthesis and has been found to be located at contig 36.

摘要

嗜水气单胞菌是一种群体感应（QS）细菌，感染人类后会导致腹泻。在此，我们报告致病性嗜水气单胞菌菌株187的基因组，该菌株拥有一个负责信号分子N-酰基高丝氨酸内酯（AHL）合成的QS基因，且已发现该基因位于重叠群36上。