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从马来西亚海岸外海水中分离出的sp. 菌株G3(2015)的全基因组序列及对磷霉素的耐药性

Whole-Genome Sequence and Fosfomycin Resistance of sp. Strain G3(2015) Isolated from Seawater off the Coast of Malaysia.

作者信息

Chan Xin-Yue, Chen Jian-Woon, Adrian Tan-Guan-Sheng, Hong Kar-Wai, Chang Chien-Yi, Yin Wai-Fong, Chan Kok-Gan

机构信息

Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.

UM Omics Centre, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Genome Announc. 2017 Mar 30;5(13):e00067-17. doi: 10.1128/genomeA.00067-17.

DOI:10.1128/genomeA.00067-17
PMID:28360153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5374227/
Abstract

sp. is a Gram-positive bacterium that is commonly found in seawater. In this study, the genome of marine sp. strain G3(2015) was sequenced using MiSeq. The fosfomycin resistant gene was identified upon bacterial genome annotation.

摘要

[具体菌种名称]是一种革兰氏阳性菌,常见于海水中。在本研究中,使用MiSeq对海洋[具体菌种名称]菌株G3(2015)的基因组进行了测序。在细菌基因组注释过程中鉴定出了磷霉素抗性基因。

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本文引用的文献

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Genome Announc. 2014 Dec 24;2(6):e01360-14. doi: 10.1128/genomeA.01360-14.
2
The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST).SEED 与利用子系统技术进行快速微生物基因组注释(RAST)。
Nucleic Acids Res. 2014 Jan;42(Database issue):D206-14. doi: 10.1093/nar/gkt1226. Epub 2013 Nov 29.
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The fosfomycin resistance gene fosB3 is located on a transferable, extrachromosomal circular intermediate in clinical Enterococcus faecium isolates.磷霉素抗性基因fosB3位于临床分离的粪肠球菌中的一个可转移的染色体外环状中间体上。
PLoS One. 2013 Oct 29;8(10):e78106. doi: 10.1371/journal.pone.0078106. eCollection 2013.
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Structural and chemical aspects of resistance to the antibiotic fosfomycin conferred by FosB from Bacillus cereus.福氏菌素抗性的结构和化学方面由蜡样芽胞杆菌的 FosB 赋予。
Biochemistry. 2013 Oct 15;52(41):7350-62. doi: 10.1021/bi4009648. Epub 2013 Sep 30.
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Mechanistic studies of FosB: a divalent-metal-dependent bacillithiol-S-transferase that mediates fosfomycin resistance in Staphylococcus aureus.机制研究 FosB:一种二价金属依赖性芽孢硫醇-S-转移酶,介导金黄色葡萄球菌对磷霉素的耐药性。
Biochem J. 2013 Apr 1;451(1):69-79. doi: 10.1042/BJ20121541.
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