Satake T, Taki F
Second Department of Internal Medicine, Nagoya University School of Medicine.
Jpn J Med. 1989 Jul-Aug;28(4):542-4. doi: 10.2169/internalmedicine1962.28.542.
These results suggest that activation of phospholipase A2 after antigen exposure triggers an increase in leukotriene synthesis resulting in inflammatory cell influx into the airway and contraction of bronchial smooth muscle. That is, it was demonstrated that inhaled antigen concerns with IgE-mast cell system, but, on the other hand it might act as non specific stimuli.
这些结果表明，抗原暴露后磷脂酶A2的激活会引发白三烯合成增加，导致炎性细胞流入气道并引起支气管平滑肌收缩。也就是说，已证明吸入性抗原与IgE-肥大细胞系统有关，但另一方面它可能作为非特异性刺激物起作用。
