全身麻醉期间角膜损伤及其水凝胶贴片保护作用
Corneal injury and its protection using hydro-gel patch during general anesthesia.
作者信息
Wan Ting, Wang Yan, Jin Xiu-Ming
机构信息
Eye Center, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China ; Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou 310009, Zhejiang Province, China.
Nursing Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China.
出版信息
Int J Ophthalmol. 2014 Dec 18;7(6):964-7. doi: 10.3980/j.issn.2222-3959.2014.06.09. eCollection 2014.
AIM
To evaluate corneal injury during general anesthesia and analyze the protective effect of medical hydro-gel eye patch in clinics.
METHODS
Seventy-six patients with 152 eyes undergoing general anesthesia were included. None had positive corneal fluorescein staining before surgery. Both eyes of each patient were analyzed, with one randomly allocated to receive medical hydro-gel eye patch, and the other to receive common adhesive tape as a control. Corneal injuries were evaluated by scoring fluorescein staining under a hand-held slit lamp immediately after surgery in postanesthesia care unit and 24h thereafter. Patients' discomforts were also evaluated.
RESULTS
Twelve eyes (15.8%) in the hydro-gel patch group and 30 eyes (39.5%) in the adhesive tape group showed corneal injury immediately after surgery. The eyes protected with hydro-gel patch showed statistically less corneal fluorescein staining than the control group. Four eyes in hydro-gel patch group and 6 eyes in adhesive tape group suffered discomfort immediately after surgery without intergroup difference and all discomforts disappeared after 24h (P=0.257). No side effect was observed in hydro-gel patch group, while 5 eyes had brow avulsion and 2 got skin itching in adhesive tape group.
CONCLUSION
Corneal injury complication was more frequent than we thought following general anesthesia. The medical hydro-gel eye patch can protect the occurrence of corneal injury following general anesthesia.
目的
评估全身麻醉期间的角膜损伤情况，并分析医用亲水凝胶眼贴在临床上的保护作用。
方法
纳入76例接受全身麻醉的患者共152只眼。所有患者术前角膜荧光素染色均为阴性。分析每位患者的双眼，其中一只随机分配接受医用亲水凝胶眼贴，另一只接受普通胶带作为对照。在麻醉后护理单元术后立即及之后24小时，通过手持裂隙灯下荧光素染色评分评估角膜损伤情况。同时评估患者的不适情况。
结果
术后即刻，亲水凝胶眼贴组有12只眼（15.8%）出现角膜损伤，胶带组有30只眼（39.5%）出现角膜损伤。使用亲水凝胶眼贴保护的眼睛角膜荧光素染色在统计学上低于对照组。亲水凝胶眼贴组有4只眼、胶带组有6只眼术后即刻出现不适，组间无差异，且所有不适在24小时后消失（P = 0.257）。亲水凝胶眼贴组未观察到副作用，而胶带组有5只眼出现眉部撕脱，2只出现皮肤瘙痒。
结论
全身麻醉后角膜损伤并发症比我们想象的更频繁。医用亲水凝胶眼贴可预防全身麻醉后角膜损伤的发生。
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