Mishra Pravakar, Sirka Chandra Sekhar, Das Rashmi Ranjan, Nanda Debasish
Department of Paediatrics, SCB Medical College , Cuttack.
Paediatr Int Child Health. 2016 Feb;36(1):72-5. doi: 10.1179/2046905514Y.0000000168. Epub 2014 Dec 26.
Zinc deficiency in patients with coeliac disease (CD) may result either from cumulative loss of insoluble zinc complexes or impaired zinc absorption because of damaged intestinal epithelial cell membrane. Zinc deficiency in CD is mild to moderate, though severe deficiency can occur in refractory or chronic CD cases with poor response to gluten-free diet (GFD). A boy aged 19 months presented with persistent diarrhoea, was diagnosed with CD, and developed severe zinc deficiency with acrodermatitis enteropathica-like disease while on GFD and zinc supplementation.
乳糜泻（CD）患者的锌缺乏可能是由于不溶性锌复合物的累积流失，或者是由于肠道上皮细胞膜受损导致锌吸收受损。CD患者的锌缺乏程度为轻度至中度，不过在对无麸质饮食（GFD）反应不佳的难治性或慢性CD病例中可能会出现严重缺乏。一名19个月大的男孩出现持续性腹泻，被诊断为CD，在接受GFD和锌补充治疗期间，发展为严重锌缺乏并伴有肠病性肢端皮炎样疾病。
