Yasuda Hajime, Fujiwara Noriko, Ishizaki Yoichi, Komatsu Norio
Division of Hematology, Department of Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Department of Hepatobiliary-Pancreatic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Pancreatology. 2015 Jan-Feb;15(1):81-3. doi: 10.1016/j.pan.2014.12.001. Epub 2014 Dec 17.
Micronutrient deficiencies such as vitamin A, iron, zinc, and selenium have been known to occur as a consequence of pancreaticoduodenectomy (PD), but vitamin B6 deficiency has not been previously reported. We report two post-PD patients who developed anemias attributed to vitamin B6 deficiency. Oral supplementations of vitamin B6 significantly improved anemias in both cases. Micronutrients including vitamin B6 should be monitored in post-PD patients, and supplementations should be carried out when necessary.
已知胰腺十二指肠切除术（PD）会导致维生素A、铁、锌和硒等微量营养素缺乏，但此前尚未有维生素B6缺乏的报道。我们报告了两名胰腺十二指肠切除术后因维生素B6缺乏而出现贫血的患者。口服补充维生素B6在两例患者中均显著改善了贫血症状。对于胰腺十二指肠切除术后的患者，应监测包括维生素B6在内的微量营养素，必要时应进行补充。
