Wu Chuan-Bin, Xi Hong, Zhou Qing, Zhang Liang-Mei
Resident, Department of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University, Shenyang, Liaoning Province, China.
Resident, Department of Pediatric Dentistry, School of Stomatology, Jilin University, Changchun, Jilin Province, China.
J Oral Maxillofac Surg. 2015 Mar;73(3):475-81. doi: 10.1016/j.joms.2014.09.025. Epub 2014 Oct 12.
Chronic sialadenitis is a common complication of radioactive iodine for the treatment of thyroid disease. The aim of this study was to describe the authors' experience with interventional sialendoscopy for the management of radioiodine-induced sialadenitis.
Twelve patients with radioiodine-induced sialadenitis treated with sialendoscopy from January 2013 through December 2013 at the Department of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University were retrospectively reviewed. Age, gender, and time to development of radioiodine-induced sialadenitis were obtained from the hospital database. All patients were asked to undergo visual analog scale (VAS) and salivary gland scintigraphy (SGS) examinations before and 6 months after surgery. A paired t test was conducted, and a P value less than .05 was considered statistically significant.
Twelve patients (15 parotid glands and 4 submandibular glands) successfully underwent interventional sialendoscopy under local anesthesia. Ductal stenosis was the most common feature identified by endoscopy. Among the 12 patients, swelling occurred in 91.7%. Compared with the preoperative score of 6, the mean VAS score 6 months after sialendoscopy was 3; 15 glands (78.9%) showed improved uptake and excretion by SGS. The postoperative VAS score was significantly lower than the preoperative VAS score (P < .05), and the postoperative SGS result was significantly higher than the preoperative SGS result (P < .05).
Interventional sialendoscopy could be an effective technique for the treatment of sialadenitis caused by radioactive iodine.
慢性涎腺炎是放射性碘治疗甲状腺疾病的常见并发症。本研究的目的是描述作者采用介入性涎腺内镜治疗放射性碘诱发的涎腺炎的经验。
回顾性分析2013年1月至2013年12月在中国医科大学口腔医学院口腔颌面外科接受涎腺内镜治疗的12例放射性碘诱发涎腺炎患者。从医院数据库中获取患者的年龄、性别以及放射性碘诱发涎腺炎的发病时间。所有患者均在手术前及术后6个月接受视觉模拟评分（VAS）和唾液腺闪烁显像（SGS）检查。进行配对t检验，P值小于0.05被认为具有统计学意义。
12例患者（15个腮腺和4个下颌下腺）在局部麻醉下成功接受了介入性涎腺内镜检查。导管狭窄是内镜检查发现的最常见特征。12例患者中，91.7%出现肿胀。与术前评分为6分相比，涎腺内镜检查后6个月的平均VAS评分为3分；15个腺体（78.9%）的SGS显示摄取和排泄改善。术后VAS评分显著低于术前VAS评分（P < 0.05），术后SGS结果显著高于术前SGS结果（P < 0.05）。
介入性涎腺内镜可能是治疗放射性碘所致涎腺炎的有效技术。
