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一例罕见的脾脏边缘区B细胞淋巴瘤误诊为复发性耳软骨炎。

A rare case of splenic marginal zone B-cell lymphoma mimicking relapsing polychondritis of the ear.

作者信息

Huang Gary J, Mendes Bryan, Sheykholeslami Kianoush

机构信息

OSF Saint Anthony Health System, Department of Surgery, University of Illinois College of Medicine at Rockford, Rockford, IL 61103, USA.

OSF Saint Anthony Health System, Department of Surgery, University of Illinois College of Medicine at Rockford, Rockford, IL 61103, USA ; OSF Specialty Clinic, 698 Featherstone Road, Guilford Square, Rockford, IL 61107, USA ; OSF Health System, Section of Otolaryngology, Head and Neck Surgery, Department of General Surgery, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA ; Department of Biomedical Science, University of Illinois College of Medicine at Rockford, Rockford, IL 61101, USA.

出版信息

Case Rep Otolaryngol. 2014;2014:139386. doi: 10.1155/2014/139386. Epub 2014 Dec 2.

DOI:10.1155/2014/139386
PMID:25544924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4269282/
Abstract

Relapsing polychondritis (RPC) is a poorly understood phenomenon associated with cartilaginous inflammation of the ear, nose, tracheobronchial tree, and peripheral joints. Many cases of RPC respond to anti-inflammatories and resolve with no further complications. However, RPC has also been linked to more insidious conditions such as malignancies, autoimmune disorders, vasculitis, or underlying infections. Given the spectrum of associated disorders, patients with RPC may need to be monitored for more insidious underlying conditions. In this case, we report a unique case of bilateral auricular inflammation and nasal inflammation mimicking RPC as the only presenting symptom of splenic marginal zone B-cell lymphoma and we survey related cases in the literature.

摘要

复发性多软骨炎(RPC)是一种了解甚少的现象,与耳、鼻、气管支气管树及外周关节的软骨炎症相关。许多RPC病例对抗炎药有反应且痊愈后无进一步并发症。然而,RPC也与更隐匿的疾病有关,如恶性肿瘤、自身免疫性疾病、血管炎或潜在感染。鉴于相关疾病的范围,RPC患者可能需要监测是否存在更隐匿的潜在疾病。在此,我们报告一例独特病例,双侧耳廓炎症和鼻腔炎症酷似RPC,却是脾边缘区B细胞淋巴瘤的唯一首发症状,并对文献中的相关病例进行综述。

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Long-term follow-up analysis of 100 patients with splenic marginal zone lymphoma treated with splenectomy as first-line treatment.对100例接受脾切除术作为一线治疗的脾边缘区淋巴瘤患者的长期随访分析。
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Patterns of bone marrow involvement in 58 patients presenting primary splenic marginal zone lymphoma with or without circulating villous lymphocytes.58例原发性脾边缘区淋巴瘤伴或不伴循环绒毛淋巴细胞患者的骨髓受累模式
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