丹麦HIV感染儿童中细小病毒4的低流行率。

Low Prevalence of Parvovirus 4 in HIV-infected Children in Denmark.

作者信息

Rosenfeldt Vibeke, Norja Päivi, Lindberg Ellinor, Jensen Lise, Hedman Lea, Väisänen Elina, Li Xuemeng, Hedman Klaus, von Linstow Marie-Louise

机构信息

From the *Department of Paediatrics, Hvidovre University Hospital, Copenhagen, Denmark; †Department of Virology, Haartman Institute, University of Helsinki, Helsinki, Finland; ‡Department of Microbiological Diagnostics and Virology, Statens Serum Institut, Copenhagen, Denmark; §Laboratory Services (HUSLAB), Helsinki University Central Hospital, Helsinki, Finland; and ¶College of Veterinary Medicine, Northeast Agricultural University, Harbin, China.

出版信息

Pediatr Infect Dis J. 2015 Jul;34(7):761-2. doi: 10.1097/INF.0000000000000642.

DOI:10.1097/INF.0000000000000642

PMID:25545184

Abstract

Parvovirus 4 (PARV4) has been associated with HIV infection in adults. We examined plasma samples from 46 HIV-infected 0-year-old to 16-year-old children for the presence of PARV4. Four children (8.7%) had detectable PARV4 IgG and 1 had IgM. The result of PARV4 polymerase chain reaction was found to be negative in all patients. PARV4 seropositivity was associated with low CD4 count but not with HIV viral load.

摘要

细小病毒4型（PARV4）与成人的HIV感染有关。我们检测了46名0岁至16岁HIV感染儿童的血浆样本中是否存在PARV4。4名儿童（8.7%）检测到PARV4 IgG，1名儿童检测到IgM。所有患者的PARV4聚合酶链反应结果均为阴性。PARV4血清阳性与低CD4计数有关，但与HIV病毒载量无关。