Tachibana Tomoyasu, Orita Yorihisa, Marunaka Hidenori, Makihara Seiichiro, Hirai Misato, Miki Kentaro, Ogawara Yuya, Ishihara Hisashi, Matsuyama Yuko, Abe-Fujisawa Iku, Shimizu Aiko, Sato Yasuharu, Nishizaki Kazunori
Department of Otolaryngology, Himeji Red Cross Hospital, Hyogo, Japan.
Department of Otolaryngology Head and Neck Surgery, Himeji Red Cross Hospital, Hyogo, Japan.
Head Neck. 2016 Apr;38 Suppl 1:E316-20. doi: 10.1002/hed.23992. Epub 2015 Jun 16.
Few studies have investigated the clinical characteristics of patients with glottic cancer without hoarseness.
This retrospective clinical study investigated 371 patients with glottic cancer.
Thirty-two of the 371 patients (8.6%) with glottic cancer first presented to hospitals with complaints other than hoarseness. Although proportions of stage I and T1 disease were significantly higher among patients without hoarseness than among those with hoarseness (p = .0036 and p = .0004, respectively), survival curves showed no significant differences between groups (p = .1334).
Patients with glottic cancer without complaints of hoarseness were diagnosed at an earlier stage than those with hoarseness. Accumulation of more cases may lead to better survival of patients with glottic cancer without hoarseness compared to those with hoarseness. Checking the larynx of patients without hoarseness or encouraging internists to check the larynx when performing gastroscopic or respiratory examinations may lead to improvement of glottic cancer prognosis. © 2015 Wiley Periodicals, Inc. Head Neck 38: E316-E320, 2016.
很少有研究调查无声音嘶哑的声门癌患者的临床特征。
这项回顾性临床研究调查了371名声门癌患者。
371名声门癌患者中有32名（8.6%）初诊时的主诉不是声音嘶哑。在无声音嘶哑的患者中，I期和T1期疾病的比例显著高于有声音嘶哑的患者（分别为p = 0.0036和p = 0.0004），但生存曲线显示两组之间无显著差异（p = 0.1334）。
无声音嘶哑主诉的声门癌患者比有声音嘶哑的患者诊断时分期更早。积累更多病例可能会使无声嘶声门癌患者比有声嘶患者有更好的生存率。检查无声嘶患者的喉部，或鼓励内科医生在进行胃镜或呼吸检查时检查喉部，可能会改善声门癌的预后。© 2015威利期刊公司。《头颈》38: E316 - E320，2016年。
