From the *Department of Diagnostic Imaging, Alpert Medical School of Brown University and Rhode Island Hospital; and †Department of Neurology, Alpert Medical School of Brown University and Butler Hospital, Providence, RI.
Clin Nucl Med. 2015 Feb;40(2):e152-6. doi: 10.1097/RLU.0000000000000608.
We report a case series of unusual I-ioflupane SPECT imaging findings. Three patients with atypical parkinsonian symptoms underwent I-ioflupane imaging to assist in diagnosis. The patients had complete or near-complete absence of striatal activity. The imaging deficit severity did not consistently correlate with the clinical deficit severity. These cases suggest that markedly abnormal uptake patterns may be seen with atypical parkinsonian syndromes. Further research is warranted to evaluate differences in I-ioflupane uptake patterns among the various parkinsonian syndromes.
我们报告了一系列不寻常的碘-123-异丙基安非他命 SPECT 成像发现。三例具有非典型帕金森病症状的患者进行了碘-123-异丙基安非他命成像以协助诊断。这些患者的纹状体活动完全或几乎完全缺失。影像学缺陷的严重程度与临床缺陷的严重程度不一致。这些病例表明，在非典型帕金森综合征中可能会出现明显异常的摄取模式。需要进一步研究以评估各种帕金森综合征之间碘-123-异丙基安非他命摄取模式的差异。
