Bijlenga G, Joubert L, De Clercq E
Ecole Nationale Vétérinaire de Lyon, Services de maladies contagieuses, France.
Ann Rech Vet. 1989;20(3):259-67.
The antiviral activity of bromovinyldeoxyuridine has been studied on the wild type of pseudorabies virus. A heterogenicity of viral populations has been observed. A resistant clone presented special characteristics both in vitro (large syncytia, round cells) and in vivo (reduced pathogenicity and immunogenic power).
已对野生型伪狂犬病病毒研究了溴乙烯基脱氧尿苷的抗病毒活性。观察到病毒群体的异质性。一个抗性克隆在体外(大的多核巨细胞、圆形细胞)和体内(致病性和免疫原性降低)均呈现出特殊特征。