Is it time to consider patients suffering from endometriosis-related infertility as "novel candidates" for targeted peri-conceptional D-chiro inositol supplementation? Hypothesis, rationale and some considerations.
作者信息
Vitagliano Amerigo, Noventa Marco, Gizzo Salvatore
机构信息
Department of Woman and Child Health, University of Padua, Padua, Italy.
出版信息
J Assist Reprod Genet. 2015 Mar;32(3):407-8. doi: 10.1007/s10815-014-0412-z. Epub 2014 Dec 30.
Abstract
摘要
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1
Is it time to consider patients suffering from endometriosis-related infertility as "novel candidates" for targeted peri-conceptional D-chiro inositol supplementation? Hypothesis, rationale and some considerations.是时候将患有子宫内膜异位症相关不孕症的患者视为孕前针对性补充D-手性肌醇的“新候选对象”了吗？假说、理论依据及一些思考。
J Assist Reprod Genet. 2015 Mar;32(3):407-8. doi: 10.1007/s10815-014-0412-z. Epub 2014 Dec 30.
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The rationale of the myo-inositol and D-chiro-inositol combined treatment for polycystic ovary syndrome.肌醇与D-手性肌醇联合治疗多囊卵巢综合征的理论依据。
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Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome.D-手性肌醇对多囊卵巢综合征的排卵及代谢影响
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[Evaluation of the treatment with D-chiro-inositol on levels of oxidative stress in PCOS patients].[D-手性肌醇治疗对多囊卵巢综合征患者氧化应激水平的评估]
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Bye-bye chiro-inositol - myo-inositol: true progress in the treatment of polycystic ovary syndrome and ovulation induction.再见了手性肌醇——米糠醇：多囊卵巢综合征和排卵诱导治疗的真正进展。
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The combined therapy myo-inositol plus D-chiro-inositol, rather than D-chiro-inositol, is able to improve IVF outcomes: results from a randomized controlled trial.联合治疗肌醇加 D-手性肌醇，而不是 D-手性肌醇，能够改善试管婴儿结局：一项随机对照试验的结果。
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Updates on the myo-inositol plus D-chiro-inositol combined therapy in polycystic ovary syndrome.多囊卵巢综合征中肌醇加D-手性肌醇联合治疗的研究进展
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The use of inositol(s) isomers in the management of polycystic ovary syndrome: a comprehensive review.肌醇异构体在多囊卵巢综合征管理中的应用：一项综述
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Reflections on inositol(s) for PCOS therapy: steps toward success.多囊卵巢综合征治疗中肌醇的思考：迈向成功的步骤
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Myo-Inositol's Role in Assisted Reproductive Technology: Evidence for Improving the Quality of Oocytes and Embryos in Patients With Polycystic Ovary Syndrome.肌醇在辅助生殖技术中的作用：改善多囊卵巢综合征患者卵母细胞和胚胎质量的证据
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Acute immunomodulatory changes during controlled ovarian stimulation: evidence from the first trial investigating the short-term effects of estradiol on biomarkers and B cells involved in autoimmunity.控制性卵巢刺激期间的急性免疫调节变化：来自第一项研究雌二醇对自身免疫相关生物标志物和B细胞短期影响试验的证据。
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Emerging evidence regarding statins use as novel endometriosis targeted treatment: real "magic pills" or "trendy" drugs? Some considerations.
Eur J Obstet Gynecol Reprod Biol. 2015 Jan;184:125-6. doi: 10.1016/j.ejogrb.2014.11.018. Epub 2014 Nov 20.
2
Effect of induced peritoneal endometriosis on oocyte and embryo quality in a mouse model.诱导性腹膜子宫内膜异位症对小鼠模型中卵母细胞和胚胎质量的影响。
J Assist Reprod Genet. 2015 Feb;32(2):263-70. doi: 10.1007/s10815-014-0390-1. Epub 2014 Nov 16.
3
Alteration in the intrafollicular thiol-redox system in infertile women with endometriosis.子宫内膜异位症不孕女性卵泡内硫醇氧化还原系统的改变。
Reproduction. 2015 Feb;149(2):155-62. doi: 10.1530/REP-14-0438. Epub 2014 Nov 5.
4
A pilot study to search possible mechanisms of ultralong gonadotropin-releasing hormone agonist therapy in IVF-ET patients with endometriosis.一项探索超长 GnRH 激动剂疗法在子宫内膜异位症患者 IVF-ET 中可能作用机制的初步研究。
J Ovarian Res. 2014 Oct 21;7:100. doi: 10.1186/s13048-014-0100-8.
5
Protein modification as oxidative stress marker in follicular fluid from women with polycystic ovary syndrome: the effect of inositol and metformin.蛋白质修饰作为多囊卵巢综合征女性卵泡液中氧化应激标志物：肌醇和二甲双胍的作用
J Assist Reprod Genet. 2014 Oct;31(10):1269-76. doi: 10.1007/s10815-014-0307-z. Epub 2014 Aug 12.
6
Could empirical low-dose-aspirin administration during IVF cycle affect both the oocytes and embryos quality via COX 1-2 activity inhibition?在体外受精周期中给予经验性低剂量阿司匹林是否会通过抑制COX 1-2活性而影响卵母细胞和胚胎质量？
J Assist Reprod Genet. 2014 Mar;31(3):261-8. doi: 10.1007/s10815-014-0174-7. Epub 2014 Jan 17.
7
Glucose transporter expression in eutopic endometrial tissue and ectopic endometriotic lesions.葡萄糖转运蛋白在正常子宫内膜组织和异位子宫内膜病灶中的表达。
J Mol Endocrinol. 2014 Feb 24;52(2):169-79. doi: 10.1530/JME-13-0194. Print 2014 Apr.
8
Low-density lipoproteins oxidation and endometriosis.低密度脂蛋白氧化与子宫内膜异位症。
Mediators Inflamm. 2013;2013:624540. doi: 10.1155/2013/624540. Epub 2013 Jun 19.
9
Follicular fluid hydrogen peroxide and lipid hydroperoxide in bovine antral follicles of various size, atresia, and dominance status.牛窦卵泡中不同大小、闭锁和优势状态的卵泡液过氧化氢和脂质氢过氧化物。
J Assist Reprod Genet. 2013 Mar;30(3):333-40. doi: 10.1007/s10815-012-9925-5. Epub 2013 Jan 15.
10
CA 125 serum values in surgically treated endometriosis patients and its relationships with anatomic sites of endometriosis and pregnancy rate.手术治疗子宫内膜异位症患者的 CA125 血清值及其与子宫内膜异位症解剖部位和妊娠率的关系。
Fertil Steril. 2011 Jan;95(1):393-6. doi: 10.1016/j.fertnstert.2010.08.043. Epub 2010 Oct 8.
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