Gurvits Grigoriy E, Lan Gloria
Grigoriy E Gurvits, Division of Gastroenterology, New York University School of Medicine/Langone Medical Center, New York, NY 10016, United States.
World J Gastroenterol. 2014 Dec 21;20(47):17819-29. doi: 10.3748/wjg.v20.i47.17819.
Enterolithiasis or formation of gastrointestinal concretions is an uncommon medical condition that develops in the setting of intestinal stasis in the presence of the intestinal diverticula, surgical enteroanastomoses, blind pouches, afferent loops, incarcerated hernias, small intestinal tumors, intestinal kinking from intra-abdominal adhesions, and stenosing or stricturing Crohn's disease and intestinal tuberculosis. Enterolithiasis is classified into primary and secondary types. Its prevalence ranges from 0.3% to 10% in selected populations. Proximal primary enteroliths are composed of choleic acid salts and distal enteroliths are calcified. Clinical presentation includes abdominal pains, distention, nausea, and vomiting of occasionally sudden but often fluctuating subacute nature which occurs as a result of the enterolith tumbling through the bowel lumen. Thorough history and physical exam coupled with radiologic imaging helps establish a diagnosis in a patient at risk. Complications include bowel obstruction, direct pressure injury to the intestinal mucosa, intestinal gangrene, intussusceptions, afferent loop syndrome, diverticulitis, iron deficiency anemia, gastrointestinal hemorrhage, and perforation. Mortality of primary enterolithiasis may reach 3% and secondary enterolithiasis 8%. Risk factors include poorly conditioned patients with significant obstruction and delay in diagnosis. Treatment relies on timely recognition of the disease and endoscopic or surgical intervention. With advents in new technology, improved outcome is expected for patients with enterolithiasis.
肠结石症或胃肠道结石形成是一种罕见的医学病症,在存在肠憩室、外科肠吻合术、盲袋、输入袢、嵌顿疝、小肠肿瘤、腹腔内粘连导致的肠扭结以及狭窄性或狭窄性克罗恩病和肠结核等导致肠淤滞的情况下发生。肠结石症分为原发性和继发性类型。在特定人群中,其患病率为0.3%至10%。近端原发性肠结石由胆酸盐组成,远端肠结石则为钙化的。临床表现包括腹痛、腹胀、恶心以及偶尔突然发作但通常呈波动的亚急性性质的呕吐,这是由于肠结石在肠腔内翻滚所致。详尽的病史和体格检查以及放射影像学检查有助于对有风险的患者做出诊断。并发症包括肠梗阻、对肠黏膜的直接压迫损伤、肠坏疽、肠套叠、输入袢综合征、憩室炎、缺铁性贫血、胃肠道出血以及穿孔。原发性肠结石症的死亡率可达3%,继发性肠结石症为8%。风险因素包括病情不佳且有严重梗阻以及诊断延误的患者。治疗依赖于对疾病的及时识别以及内镜或手术干预。随着新技术的出现,预计肠结石症患者的治疗效果将会改善。