Erol Nurdan, Karaagac Aysu Turkmen, Kounis Nicholas G
Nurdan Erol, Siyami Ersek Thorax and Cardiovascular Surgery Training and Research Hospital, Pediatric Cardiology Clinic, 34668 Uskudar, Istanbul, Turkey.
World J Cardiol. 2014 Dec 26;6(12):1285-9. doi: 10.4330/wjc.v6.i12.1285.
Polycystic ovary syndrome is characterized by ovulatory dysfunction, androgen excess and polycystic ovaries and is associated with hypertension, diabetes, metabolic syndrome and cardiovascular events. Oral contraceptives constitute first-line treatment, particularly when symptomatic hyperandrogenism is present. However, these drugs are associated with cardiovascular events and hypersensitivity reactions that pose problem in differential diagnosis and therapy. We present a 14 year-old female with polycystic ovary syndrome taking oral contraceptive and suffering from recurrent coronary ischemic attacks with increased eosinophils, and troponin levels suggesting Kounis syndrome.
多囊卵巢综合征的特征是排卵功能障碍、雄激素过多和多囊卵巢，并与高血压、糖尿病、代谢综合征及心血管事件相关。口服避孕药是一线治疗药物，尤其是在出现有症状的高雄激素血症时。然而，这些药物与心血管事件及过敏反应相关，这给鉴别诊断和治疗带来了问题。我们报告一名14岁患有多囊卵巢综合征的女性，她正在服用口服避孕药，反复出现冠状动脉缺血发作，伴有嗜酸性粒细胞增多以及肌钙蛋白水平升高，提示为库尼斯综合征。
