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复发性疾病中的外阴癌与HPV疫苗接种

Vulval cancer and HPV vaccination in recurrent disease.

作者信息

Gustafson L W, Gade Melina, Blaakær Jan

机构信息

Department of Obstetrics and Gynecology, Aarhus University Hospital Brendstrupgaardsvej 100, 8200, Aarhus N, Denmark.

出版信息

Clin Case Rep. 2014 Dec;2(6):243-6. doi: 10.1002/ccr3.93. Epub 2014 Nov 17.

DOI:10.1002/ccr3.93
PMID:25548622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4270702/
Abstract

A woman diagnosed with a recurrent vulval carcinoma after initial treatment with radiochemotherapy is presented. After three additional relapses she was vaccinated with Gardasil. She has had no relapses in her vulvar area for 39 months and an overall progression-free survival of almost 24 months.

摘要

本文介绍了一名在接受放化疗初始治疗后被诊断为复发性外阴癌的女性。在又经历三次复发后，她接种了加德西疫苗。她的外阴区域已39个月未复发，总体无进展生存期近24个月。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df02/4270702/704e897197a4/ccr30002-0243-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df02/4270702/7b35affd74c2/ccr30002-0243-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df02/4270702/704e897197a4/ccr30002-0243-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df02/4270702/7b35affd74c2/ccr30002-0243-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df02/4270702/704e897197a4/ccr30002-0243-f2.jpg

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本文引用的文献

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EUROGIN 2011 roadmap on prevention and treatment of HPV-related disease.EUROGIN 2011 关于预防和治疗 HPV 相关疾病的路线图。
Int J Cancer. 2012 Nov 1;131(9):1969-82. doi: 10.1002/ijc.27650. Epub 2012 Jul 2.
2
Persistence of immune response to HPV-16/18 AS04-adjuvanted cervical cancer vaccine in women aged 15-55 years.15至55岁女性对HPV-16/18 AS04佐剂宫颈癌疫苗免疫反应的持久性
Hum Vaccin. 2011 Sep;7(9):958-65. doi: 10.4161/hv.7.9.15999. Epub 2011 Sep 1.
3
Early effect of the HPV vaccination programme on cervical abnormalities in Victoria, Australia: an ecological study.
澳大利亚维多利亚州 HPV 疫苗接种计划对宫颈异常的早期影响：一项生态学研究。
Lancet. 2011 Jun 18;377(9783):2085-92. doi: 10.1016/S0140-6736(11)60551-5.
4
End-of-study safety, immunogenicity, and efficacy of quadrivalent HPV (types 6, 11, 16, 18) recombinant vaccine in adult women 24-45 years of age.四价人乳头瘤病毒（6、11、16、18 型）重组疫苗在 24-45 岁成年女性中的研究结束安全性、免疫原性和有效性。
Br J Cancer. 2011 Jun 28;105(1):28-37. doi: 10.1038/bjc.2011.185. Epub 2011 May 31.
5
Recurrent laryngeal papillomatosis: successful treatment with human papillomavirus vaccination.复发性喉乳头状瘤：人乳头状瘤病毒疫苗接种的成功治疗。
Arch Dis Child. 2011 May;96(5):476-7. doi: 10.1136/adc.2010.198184. Epub 2011 Jan 10.
6
HPV - immune response to infection and vaccination.HPV - 感染和疫苗接种的免疫反应。
Infect Agent Cancer. 2010 Oct 20;5:19. doi: 10.1186/1750-9378-5-19.
7
Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia.二期临床试验中咪喹莫特和 HPV 治疗性疫苗在治疗外阴上皮内瘤变患者中的应用。
Br J Cancer. 2010 Mar 30;102(7):1129-36. doi: 10.1038/sj.bjc.6605611. Epub 2010 Mar 16.
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Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia.针对人乳头瘤病毒16型癌蛋白的疫苗用于外阴上皮内瘤变
N Engl J Med. 2009 Nov 5;361(19):1838-47. doi: 10.1056/NEJMoa0810097.
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