Heindl Ludwig M, Siebelmann Sebastian, Dietlein Thomas, Hüttmann Gereon, Lankenau Eva, Cursiefen Claus, Steven Philipp
a Department of Ophthalmology , University of Cologne , Cologne , Germany and.
b Institute of Biomedical Optics, University of Luebeck , Luebeck , Germany , and.
Curr Eye Res. 2015;40(12):1288-91. doi: 10.3109/02713683.2014.995311. Epub 2014 Dec 30.
Ab interno glaucoma surgery, such as trabecular aspiration or ab interno trabeculotomy, has been introduced as an alternative, non-filtering procedure to lower intraocular pressure in glaucoma patients. The purpose of the present study was to assess the feasibility of intraoperative spectral domain optical coherence tomography (iOCT) for improving ab interno glaucoma surgery.
Intraoperative optical coherence tomography was performed to visualize the anterior chamber angle, the aspiration canula during trabecular aspiration, and the trabectome device during ab interno trabeculotomy. A commercially available 840-nm iOCT was used in a clinical setting, a 1310-nm spectral-domain OCT in an experimental setting.
In the clinical setting using the 840-nm iOCT, visualization of the aspiration canula and the trabectome device was possible, however, with rather limited visibility of the chamber angle and the trabecular meshwork. In the experimental setting, the 1310-nm OCT enabled excellent visualization of the chamber angle and detailed evaluation of the instrument-trabecular meshwork relation.
Intraoperative use of optical coherence tomography may be helpful for ab interno glaucoma surgery. Adjustments of the commercially available iOCT, including longer wavelengths and oblique scanning options, are necessary for the clinical use.
内路青光眼手术,如小梁抽吸术或内路小梁切开术,已被引入作为降低青光眼患者眼压的一种替代性非滤过性手术。本研究的目的是评估术中光谱域光学相干断层扫描(iOCT)用于改善内路青光眼手术的可行性。
进行术中光学相干断层扫描以可视化前房角、小梁抽吸术中的抽吸套管以及内路小梁切开术中的小梁切开刀装置。在临床环境中使用市售的840纳米iOCT,在实验环境中使用1310纳米光谱域OCT。
在使用840纳米iOCT的临床环境中,可以可视化抽吸套管和小梁切开刀装置,然而,前房角和小梁网的可视性相当有限。在实验环境中,1310纳米OCT能够出色地可视化前房角并详细评估器械与小梁网的关系。
术中使用光学相干断层扫描可能有助于内路青光眼手术。对于临床应用,需要对市售iOCT进行调整,包括更长波长和斜向扫描选项。