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[临床医生在细菌学实验室实施基质辅助激光解吸电离飞行时间质谱(MALDI-TOF/MS)有哪些益处?]

[Which benefits for the clinician to implement MALDI-TOF/MS in the bacteriology laboratory?].

作者信息

Riat A, Cherkaoui A, Emonet S, Greub G, Schrenzel J

机构信息

Laboratoire de bactériologie, HUG, Genève.

出版信息

Rev Med Suisse. 2014 Nov 12;10(450):2149-54.

PMID:25549376
Abstract

Mass spectrometry (MALDI-TOF/MS) is a recent technology especially adapted to identify microbial pathogens. It has rapidly established itself as a must for most medical bacteriology laboratories. Its ease of use and speed of execution typically permit providing pathogen identification one day earlier to the clinicians. MALDI-TOF/MS facilitates identification of filamentous fungi and mycobacteria that require particular lab expertise when using conventional methods. This paper highlights the multiple advantages that MALDI-TOF/MS can bring to the physicians in their practice.

摘要

质谱分析法(基质辅助激光解吸电离飞行时间质谱法,MALDI-TOF/MS)是一项新近的技术,特别适用于鉴定微生物病原体。它已迅速成为大多数医学细菌学实验室的必备技术。其易用性和执行速度通常能让临床医生提前一天获得病原体鉴定结果。MALDI-TOF/MS有助于鉴定丝状真菌和分枝杆菌,而使用传统方法鉴定这些微生物需要特定的实验室专业技能。本文重点介绍了MALDI-TOF/MS在医生临床实践中所能带来的诸多优势。

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