Université de Lille, Sciences et Technologies, EA 4478, Chimie Moléculaire et Formulation, F-59655 Villeneuve d'Ascq Cedex, France.
Beilstein J Org Chem. 2014 Nov 7;10:2603-22. doi: 10.3762/bjoc.10.273. eCollection 2014.
Host-guest chemistry is useful for the construction of nanosized objects. Some of the widely used hosts are probably the cyclodextrins (CDs). CDs can form water-soluble complexes with numerous hydrophobic compounds. They have been widespread used in medicine, drug delivery and are of interest for the biocides encapsulation. Indeed, this enables the development of more or less complex systems that release antimicrobial agents with time. In this paper, the general features of CDs and their applications in the field of biocides have been reviewed. As the key point is the formation of biocide-CD inclusion complexes, this review deals with this in depth and the advantages of biocide encapsulation are highlighted throughout several examples from the literature. Finally, some future directions of investigation have been proposed. We hope that scientists studying biocide applications receive inspiration from this review to exploit the opportunities offered by CDs in their respective research areas.
主客体化学在纳米物体的构建中很有用。一些广泛使用的主体可能是环糊精（CDs）。CD 可以与许多疏水性化合物形成水溶性配合物。它们已广泛应用于医学、药物输送领域，并对杀生物剂的封装感兴趣。事实上，这使得能够开发出或多或少具有复杂系统的释放抗菌剂的时间。在本文中，综述了 CD 的一般特征及其在杀生物剂领域的应用。由于关键是杀生物剂-CD 包合物的形成，因此本文对此进行了深入探讨，并通过文献中的几个实例强调了杀生物剂封装的优势。最后，提出了一些未来的研究方向。我们希望研究杀生物剂应用的科学家从这篇综述中获得灵感，在各自的研究领域中利用 CDs 提供的机会。
