ElSheikha Ola Z, Abdelhakim Mohamad A S E, Elhilali Hala M, Kassem Rehab R
Department of Pediatric Ophthalmology, Abo El Reish Kasr Al Ainy Pediatric Hospital, Cairo University, Cairo, Egypt.
Acta Ophthalmol. 2015 Aug;93(5):e366-e371. doi: 10.1111/aos.12634. Epub 2015 Jan 4.
The aim of this study was to assess the efficacy of viscotrabeculotomy in the management of congenital glaucoma as compared to conventional trabeculotomy, in Egyptian infants.
This is a prospective interventional randomized comparative study in which patients with primary congenital glaucoma were randomly allocated to either group A or B; viscotrabeculotomy (VT); and trabeculotomy (T), respectively. Patients were followed up regarding intra-ocular pressure (IOP), cup/disc (C/D) ratio and horizontal corneal diameter (HCD) for 6 months. A probability value (p value) <0.05 was considered significant.
Twenty-one eyes in group A and 20 eyes in group B were enrolled in the study. The mean preoperative IOP was 23.5 and 24.3 mmHg in the VT and T groups, respectively. Postoperatively, IOP dropped at six months to 14.7 and 17 mmHg in the VT and T groups, respectively. That was significant in either group when compared to preoperative IOP, but not significant between both groups at the same point of comparison.
Both techniques were equally effective in the reduction in IOP in the management of congenital glaucoma, but viscotrabeculotomy did not appear to add more benefit to the surgical outcome than classic trabeculotomy.
本研究旨在评估在埃及婴儿中，与传统小梁切开术相比，粘弹剂小梁切开术治疗先天性青光眼的疗效。
这是一项前瞻性干预性随机对照研究，将原发性先天性青光眼患者随机分为A组或B组，分别接受粘弹剂小梁切开术（VT）和小梁切开术（T）。对患者的眼压（IOP）、杯盘比（C/D）和角膜水平直径（HCD）进行6个月的随访。概率值（p值）<0.05被认为具有统计学意义。
A组21只眼和B组20只眼纳入研究。VT组和T组术前平均眼压分别为23.5 mmHg和24.3 mmHg。术后6个月，VT组和T组眼压分别降至14.7 mmHg和17 mmHg。与术前眼压相比，两组均有显著下降，但在同一比较点两组之间差异无统计学意义。
在先天性青光眼的治疗中，两种技术在降低眼压方面同样有效，但与传统小梁切开术相比，粘弹剂小梁切开术似乎并未给手术结果带来更多益处。
